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Best otc sleep aids - Holiday Sale 2025

Last Updated - December 14, 2025

1
Best Choice
17% Off

✖
Our rankings are cleverly generated from the algorithmic analysis of thousands of customer reviews about products, brands, merchant’s customer service level, popularity, trends and more. The rankings reflect our opinion and should be a good starting point for shopping.

Unisom
17% Off

Unisom Nighttime Sleep-Aid Gels, Diphenhydramine HCI 50mg, 100 Count, 2 pk

Unisom

$28.88

$34.98
(17% Off)

More Details
Main highlights
- TRUST UNISOM, THE SLEEP EXPERT: The Pharmacist Recommended OTC Sleep-Aid Brand Data represents brand/product selections from the 2019 Pharmacy Times Survey of Pharmacists' OTC Recommendations
- NON-HABIT FORMING: Liquid-filled SoftGels are safe if used as directed, non-habit forming and help you sleep soundly
- INCLUDES: Two (2) bottles with 100 SoftGels of Unisom SleepGels Nighttime Sleep-aid; one SoftGel per dose
- FIND A NIGHTTIME SLEEP SOLUTION THAT'S RIGHT FOR YOU: Millions of people turn to Unisom for a restful night's sleep; Unisom SleepGels, SleepTabs, SleepMinis, SleepMelts or PM Pain can help you take on your day
- A STRESSFUL DAY DESERVES A RESTFUL NIGHT: Unisom helps you fall asleep fast and get a good night's sleep to recharge and restore
$28.88
$34.98 (17% Off)
2
10% Off

✖
Our rankings are cleverly generated from the algorithmic analysis of thousands of customer reviews about products, brands, merchant’s customer service level, popularity, trends and more. The rankings reflect our opinion and should be a good starting point for shopping.

Unisom
10% Off

Unisom SleepTabs, Nighttime Sleep-aid, Doxylamine Succinate, 80 Tablets, 2 pk

Unisom

$25.15

$27.98
(10% Off)

More Details
Main highlights
- TRUST UNISOM, THE SLEEP EXPERT: The #1 Pharmacist Recommended OTC Sleep-Aid Brand* *Data represents brand/product selections from the 2019 Pharmacy Times Survey of Pharmacists' OTC Recommendations
- NON-HABIT FORMING: SleepTabs are safe if used as directed, non-habit forming and help you sleep through the night and feel recharged without grogginess or lingering side effects
- INCLUDES: Two (2) bottles with 80 Tablets of Unisom SleepTabs Nighttime Sleep-aid; one tablet per dose
- FIND A NIGHTTIME SLEEP SOLUTION RIGHT FOR YOU: Millions of people turn to Unisom for a restful night's sleep; Unisom SleepGels, SleepTabs, SleepMinis, SleepMelts or PM Pain can help you take on your day
- FALL ASLEEP 33% FASTER*: Effective sleep aid helps you fall asleep faster* and stay asleep *versus placebo in a clinical study
$25.15
$27.98 (10% Off)
3

✖
Our rankings are cleverly generated from the algorithmic analysis of thousands of customer reviews about products, brands, merchant’s customer service level, popularity, trends and more. The rankings reflect our opinion and should be a good starting point for shopping.

HealthA2Z

HealthA2Z Sleep Aid, Diphenhydramine Softgels, 50mg, Supports Deeper, Restful Sleeping (250 Counts)

HealthA2Z

$9.99

More Details
Main highlights
- 🔵 Trusted Nighttime Relief: Suitable for adults and children 12 years and older; take 1 softgel at bedtime if needed.
- 🔵 Large Count for Value: With 250 softgels per bottle, you’ll have a convenient supply for regular use.
- 🔵 Fall Asleep Fast & Stay Asleep: Helps you drift off more easily and wake up feeling refreshed.
- 🔵 Effective Sleep Support: Each softgel contains 50 mg of Diphenhydramine HCl, a widely used active ingredient for occasional sleeplessness.
- 🔵 Easy-to-Swallow Softgels: Liquid-filled softgel format allows for faster absorption and comfortable ingestion.
$9.99
4

✖
Our rankings are cleverly generated from the algorithmic analysis of thousands of customer reviews about products, brands, merchant’s customer service level, popularity, trends and more. The rankings reflect our opinion and should be a good starting point for shopping.

Amazon Basic Care

Amazon Basic Care Nighttime Sleep Aid Tablets for Adults, Doxylamine Succinate 25 mg, 96 Count

Amazon Basic Care

$11.74

More Details
Main highlights
- THE ACTIVE INGREDIENT in Amazon Basic Care Sleep Aid Tablets is doxylamine succinate 25 mg, a nighttime sleep aid which compares to the active ingredient in Unisom SleepTabs
- TESTED & EFFECTIVE: Clinically tested and proven effective, doxylamine succinate 25 mg sleep aid tablets are for adults and children ages 12 years and older
- NIGHTTIME SLEEP AID: With just one tablet per dose, Amazon Basic Care Sleep Aid Tablets, Doxylamine Succinate Tablets 25 mg help to reduce difficulty in falling asleep. Use as a nighttime sleep aid
- FOCUS ON SLEEP: With a single one-tablet dose, Amazon Basic Care Sleep Aid Tablets with doxylamine succinate 25 mg as the active ingredient help reduce difficulty in falling asleep. This nighttime sleep aid contains no pain reliever and is gluten free
- FALL ASLEEP: Sleep is important. One tablet per dose helps to reduce difficulty falling asleep. Gluten free
$11.74
5
Best Value
30% Off

✖
Our rankings are cleverly generated from the algorithmic analysis of thousands of customer reviews about products, brands, merchant’s customer service level, popularity, trends and more. The rankings reflect our opinion and should be a good starting point for shopping.

Unisom
30% Off

Unisom SleepTabs, Nighttime Sleep-aid, Doxylamine Succinate, 80 Tablets

Unisom

$13.98

$19.99
(30% Off)

More Details
Main highlights
- TRUST UNISOM, THE SLEEP EXPERT: The Pharmacist Recommended OTC Sleep-Aid Brand* *Data represents brand/product selections from the 2019 Pharmacy Times Survey of Pharmacists' OTC Recommendations
- NON-HABIT FORMING: SleepTabs are safe if used as directed, non-habit forming and help you sleep through the night and feel recharged without grogginess or lingering side effects
- INCLUDES: One (1) 80-count bottle of Unisom SleepTabs Nighttime Sleep-aid; one tablet per dose
- FIND A NIGHTTIME SLEEP SOLUTION RIGHT FOR YOU: Millions of people turn to Unisom for a restful night's sleep; Unisom SleepGels, SleepTabs, SleepMinis, SleepMelts or PM Pain can help you take on your day
- FALL ASLEEP 33% FASTER*: Effective sleep aid helps you fall asleep faster* and stay asleep *versus placebo in a clinical study
$13.98
$19.99 (30% Off)

Best otc sleep aids - Holiday Sale 2025

Unisom Nighttime Sleep-Aid Gels, Diphenhydramine HCI 50mg, 100 Count, 2 pk

Unisom SleepTabs, Nighttime Sleep-aid, Doxylamine Succinate, 80 Tablets, 2 pk

HealthA2Z Sleep Aid, Diphenhydramine Softgels, 50mg, Supports Deeper, Restful Sleeping (250 Counts)

Amazon Basic Care Nighttime Sleep Aid Tablets for Adults, Doxylamine Succinate 25 mg, 96 Count

Unisom SleepTabs, Nighttime Sleep-aid, Doxylamine Succinate, 80 Tablets

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