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Best over counter medications - January 2026

Last Updated - January 21, 2026

1
Best Choice
25% Off

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Our rankings are cleverly generated from the algorithmic analysis of thousands of customer reviews about products, brands, merchant’s customer service level, popularity, trends and more. The rankings reflect our opinion and should be a good starting point for shopping.

Boiron
25% Off

Boiron Oscillococcinum for Relief from Flu-Like Symptoms of Body Aches, Headache, Fever, Chills, and Fatigue - 30 Doses

Picked by 431 people in the last week

Boiron

$25.46

$33.99
(25% Off)

More Details
Main highlights
- THE BOIRON PROMISE: We believe there’s a better way to feel better. Since 1932, we’ve been dedicated to providing the purest medicines made from earth’s best resources
- SHORTEN YOUR SYMPTOMS: Oscillo has been shown in clinical studies to help reduce both the duration and the severity of flu-like symptoms when taken at the onset.* Non-drowsy, easy-to-take relief
- HSA & FSA eligible: Oscillococcinum is HSA & FSA eligible
- HOMEOPATHIC FLU RELIEF: Oscillococcinum works with your body to help relieve body aches, headache, fever, chills, and fatigue.* Ideal for ages 2 and up, take at the first sign of flu-like symptoms
- HOLISTIC SUPPORT: Looking for homeopathic flu relief for the whole family? Oscillococcinum’s meltaway pellets dissolve easily in the mouth; no water, chewing, or swallowing required
- A BETTER WAY TO FEEL BETTER: Homeopathic medicines use highly diluted botanical, biological, or mineral substances to relieve symptoms. They work with your body without the risk of known drug interactions
$25.46
$33.99 (25% Off)
2

✖
Our rankings are cleverly generated from the algorithmic analysis of thousands of customer reviews about products, brands, merchant’s customer service level, popularity, trends and more. The rankings reflect our opinion and should be a good starting point for shopping.

Advil

Advil Liqui-Gels minis Pain Reliever and Fever Reducer, Pain Medicine for Adults with Ibuprofen 200mg for Pain Relief - 200 Liquid Filled Capsules

Advil

$21.94

$23.49
(7% Off)

More Details
Main highlights
- Take these Advil mini Liqui-Gels as directed - the perfect addition to your college dorm room essentials
- Pain reliever and fever reducer for adults designed for fast absorption, with the same strength as regular size Advil Liqui-Gels
- One bottle of 200 Advil Liqui-Gels minis Pain Reliever and Fever Reducer Liquid Filled Capsules, Pain Medicine for Adults with Ibuprofen 200mg for Pain Relief
- Liqui-Gel Minis are easy to swallow - the perfect addition to your college dorm room essentials
- Headache medicine, back pain medicine and joint or minor arthritis pain reliever that are faster and stronger on tough pain than Tylenol Rapid Release Gels
- HSA and FSA eligible product
- Fever medicine and headache pain relief, period pain relief, joint pain medicine and back pain medication for adults and children 12 years and older
$21.94
$23.49 (7% Off)
3
25% Off

✖
Our rankings are cleverly generated from the algorithmic analysis of thousands of customer reviews about products, brands, merchant’s customer service level, popularity, trends and more. The rankings reflect our opinion and should be a good starting point for shopping.

Tylenol
25% Off

Tylenol Extra Strength Acetaminophen Rapid Release Gels, Pain Reliever & Fever Reducer, Gelcaps with Laser-Drilled Holes for Fast Release, Gentle on Stomach, 500 mg Per Gelcap, 100 Count OTC Medicine

Tylenol

$12.47

$16.59
(25% Off)

More Details
Main highlights
- Rapid-release technology: Laser-drilled holes in each gelcap release acetaminophen faster for extra strength pain relief; gelcaps are gentle on the stomach and suitable for adults and children 12 years and older
- Multi-symptom support: Use as a fever reducer and to relieve headache, backache, muscle aches, arthritis pain, toothache, and joint discomfort; also helps with menstrual and premenstrual cramps and pain from the common cold or flu
- Fast-acting relief: Tylenol Extra Strength Rapid Release Gels feature 500 mg acetaminophen per gelcap to temporarily relieve minor aches and pains from headache, backache, arthritis, toothache, menstrual cramps, muscle aches, and fever; 100-count
- Dosage instructions: Adults and children 12 years and older take two gelcaps every six hours while symptoms last; do not exceed six gelcaps in 24 hours; always follow the label directions for safe use of acetaminophen and dosing guidance
- Doctor-recommended brand: Choose Tylenol, the #1 doctor-recommended brand for pain relief and fever reduction based on 2021 IQVIA survey; over-the-counter medication with 500 mg acetaminophen per gelcap that’s gentle on the stomach
$12.47
$16.59 (25% Off)
4
Best Value
29% Off

✖
Our rankings are cleverly generated from the algorithmic analysis of thousands of customer reviews about products, brands, merchant’s customer service level, popularity, trends and more. The rankings reflect our opinion and should be a good starting point for shopping.

Tylenol
29% Off

Tylenol Extra Strength Acetaminophen Rapid Release Gels, Pain Reliever & Fever Reducer, Gelcaps with Laser-Drilled Holes for Fast Release, Gentle on Stomach, 500 mg Per Gelcap, 100 Count OTC Medicine

Tylenol

$11.85

$16.59
(29% Off)

More Details
Main highlights
- Rapid-release technology: Laser-drilled holes in each gelcap release acetaminophen faster for extra strength pain relief; gelcaps are gentle on the stomach and suitable for adults and children 12 years and older
- Multi-symptom support: Use as a fever reducer and to relieve headache, backache, muscle aches, arthritis pain, toothache, and joint discomfort; also helps with menstrual and premenstrual cramps and pain from the common cold or flu
- Fast-acting relief: Tylenol Extra Strength Rapid Release Gels feature 500 mg acetaminophen per gelcap to temporarily relieve minor aches and pains from headache, backache, arthritis, toothache, menstrual cramps, muscle aches, and fever; 100-count
- Dosage instructions: Adults and children 12 years and older take two gelcaps every six hours while symptoms last; do not exceed six gelcaps in 24 hours; always follow the label directions for safe use of acetaminophen and dosing guidance
- Doctor-recommended brand: Choose Tylenol, the #1 doctor-recommended brand for pain relief and fever reduction based on 2021 IQVIA survey; over-the-counter medication with 500 mg acetaminophen per gelcap that’s gentle on the stomach
$11.85
$16.59 (29% Off)
5

✖
Our rankings are cleverly generated from the algorithmic analysis of thousands of customer reviews about products, brands, merchant’s customer service level, popularity, trends and more. The rankings reflect our opinion and should be a good starting point for shopping.

Vicks

VICKS DayQuil & NyQuil SEVERE Co-Pack, Cold & Flu Medicine, Powerful Relief for Headache, Fever, Sore Throat, Minor Aches & Pains, Congestion, Sinus Pressure, Stuffy Nose, and Cough, 48 LiquiCaps

Vicks

$20.97

$21.99
(5% Off)

More Details
Main highlights
- WORLD'S #1 SELLING OTC COUGH AND COLD BRAND. Vicks has been trusted for over 125 years to relieve your worst cold & flu symptoms.
- RELIEF YOU TRUST, DAY & NIGHT. Use non-drowsy DayQuil SEVERE for daytime relief and at night try NyQuil SEVERE for fast relief so you can rest.
- PROVEN RELIEF FOR YOUR WORST COLD & FLU SYMPTOMS. Life doesn’t stop when you have a cold. NyQuil and DayQuil SEVERE tackle your most bothersome cold & flu symptom
- POWERFUL COLD & FLU RELIEF. DayQuil and NyQuil SEVERE temporarily relieve common cold & flu symptoms
- NOTHING WORKS FASTER. Just one dose starts working fast to provide effective cold & flu relief
$20.97
$21.99 (5% Off)

Best over counter medications - January 2026

Boiron Oscillococcinum for Relief from Flu-Like Symptoms of Body Aches, Headache, Fever, Chills, and Fatigue - 30 Doses

Advil Liqui-Gels minis Pain Reliever and Fever Reducer, Pain Medicine for Adults with Ibuprofen 200mg for Pain Relief - 200 Liquid Filled Capsules

Tylenol Extra Strength Acetaminophen Rapid Release Gels, Pain Reliever & Fever Reducer, Gelcaps with Laser-Drilled Holes for Fast Release, Gentle on Stomach, 500 mg Per Gelcap, 100 Count OTC Medicine

Tylenol Extra Strength Acetaminophen Rapid Release Gels, Pain Reliever & Fever Reducer, Gelcaps with Laser-Drilled Holes for Fast Release, Gentle on Stomach, 500 mg Per Gelcap, 100 Count OTC Medicine

VICKS DayQuil & NyQuil SEVERE Co-Pack, Cold & Flu Medicine, Powerful Relief for Headache, Fever, Sore Throat, Minor Aches & Pains, Congestion, Sinus Pressure, Stuffy Nose, and Cough, 48 LiquiCaps

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VICKS DayQuil & NyQuil SEVERE Co-Pack, Cold & Flu Medicine, Powerful Relief for Headache, Fever, Sore Throat, Minor Aches & Pains, Congestion, Sinus Pressure, Stuffy Nose, and Cough, 48 LiquiCaps

Imodium A-D Fast-Acting Anti-Diarrheal Softgels, Loperamide HCl 2 mg, Travel Essential Diarrhea Relief Medicine for Adults, 24 Count, Anti Diarrhea Pills, Ages 12+, Easy to Swallow

Imodium A-D Fast-Acting Anti-Diarrheal Softgels, Loperamide HCl 2 mg, Travel Essential Diarrhea Relief Medicine for Adults, 24 Count, Anti Diarrhea Pills, Ages 12+, Easy to Swallow

Advil Liqui-Gels minis Pain Reliever and Fever Reducer, Pain Medicine for Adults with Ibuprofen 200mg for Pain Relief - 200 Liquid Filled Capsules

Pepto Bismol Liquid, Upset Stomach Relief, Nausea Relief, Heartburn Relief, Indigestion Relief, Anti Diarrhea Medication for Adults - 5 Symptom Fast Relief, 2x12 oz (Packaging May Vary)

Amazon Basic Care Loperamide Hydrochloride Tablets, 2 mg, Anti-Diarrheal, 24 Count (Pack of 1) (Packaging may vary)

Amazon Basic Care Loperamide Hydrochloride Tablets, 2 mg, Anti-Diarrheal, 24 Count (Pack of 1) (Packaging may vary)

Ricola MAX Throat Care Honey Lemon Drops with Extra Menthol Liquid Center - Maximum Cough and Sore Throat Relief for Cold & Flu Symptoms - 34 Count - Herbal Lozenges

Ricola MAX Throat Care Honey Lemon Drops with Extra Menthol Liquid Center - Maximum Cough and Sore Throat Relief for Cold & Flu Symptoms - 34 Count - Herbal Lozenges

Icy Hot Original Pain Relief Nighttime Recovery No-Mess Roll-On Applicator, Fast-Acting Pain Relief with Menthol 8% for Backaches, Joints, Muscle Strains and Arthritis, Lavender Scent, 2 oz

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