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Best flea sprays for dogs - Holiday Sale 2025

Last Updated - December 14, 2025

1
Best Choice

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Our rankings are cleverly generated from the algorithmic analysis of thousands of customer reviews about products, brands, merchant’s customer service level, popularity, trends and more. The rankings reflect our opinion and should be a good starting point for shopping.

K9 Advantix

K9 Advantix II Large Dog Vet-Recommended Flea, Tick & Mosquito Treatment & Prevention | Dogs 21 - 55 lbs. | 4-Mo Supply

K9 Advantix

$57.48

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Main highlights
- Vet-recommended formula kills & repels on contact so fleas don’t have to bite your dog to die
- No prescription needed
- Kills fleas within 12 hours of application
- K9 Advantix II Large Dog 30-day treatment & prevention protects dogs 21-55 lbs. from fleas, ticks, mosquitoes, biting flies and lice
- Easy-to-apply topical treatment is fragrance-free and waterproof after 24 hours
$57.48
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Our rankings are cleverly generated from the algorithmic analysis of thousands of customer reviews about products, brands, merchant’s customer service level, popularity, trends and more. The rankings reflect our opinion and should be a good starting point for shopping.

Wondercide

Wondercide - Flea, Tick & Mosquito Spray for Dogs, Cats, and Home - Control, Prevention, Treatment - with Natural Essential Oils - Pet and Family Safe - Peppermint 16 oz

Wondercide

$26.99

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Main highlights
- TREAT NATURE WITH NATURE. When used as directed, a safe and effective alternative to collars, pills, chewables, and drops harnesses the power of nature.Enjoy peace of mind knowing your pets and home are protected with our non-harsh formula.
- SAFE FOR DOGS, CATS OF ALL AGES WHEN USED AS DIRECTED. Gentle enough to use on puppies, kittens, and senior pets when used as directed. Powerful enough to fully eliminate pests on the skin and fur. Safe to use around the entire family, and kid-safe, when used as directed. Mom owned, Mom approved.
- POWERFULLY EFFECTIVE. Powered by nature and proven to work. Give your pet the advantage in protection against fleas and ticks with our non-harsh formula. Cruelty free and USA Made with U.S. and global components. Read entire label prior to use. Do not soak pet. Test a small area on the back of the neck 1 hour prior to full body application.
- KILLS & REPELS. Using natural essential oils, this spray is proven to kill by contact, repel, and prevent 98-100% of fleas, ticks and mosquitoes in laboratory testing. It breaks the flea life cycle by eliminating eggs, larvae, and adults.
- 3-IN-1 PLANT POWERED SOLUTION. For dogs, cats, and home! A home remedy that kills fleas throughout the house on carpet, furniture, bedding, and flooring. Also a repellent in pet environments like dog kennels or cat condos. Invigorating Peppermint scent freshens homes.
$26.99
3
Best Value

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Our rankings are cleverly generated from the algorithmic analysis of thousands of customer reviews about products, brands, merchant’s customer service level, popularity, trends and more. The rankings reflect our opinion and should be a good starting point for shopping.

Vet's Best

Vet’s Best Indoor Flea and Tick Spray – Dog Flea and Tick Treatment for Home, Plant-Based Formula with Natural Oils, Kills Fleas, Eggs & Ticks on Contact, Made in USA, 32 oz

Vet's Best

$15.48

More Details
Main highlights
- PROVEN EFFECTIVE: Our flea and tick spray is scientifically proven to be effective in killing and repelling fleas, ticks, and mosquitoes; with its powerful formulation, you can trust it to provide reliable and long-lasting protection for your furry friend
- MADE IN THE USA: Proudly manufactured in the USA using high-quality domestic and globally sourced ingredients. This flea and tick spray is vet-formulated for safety, effectiveness, and peace of mind—designed to protect pets and your home naturally.
- FLEA & TICK SPRAY FOR HOME & DOG: Our flea and tick spray for dogs is gentle enough to use on dogs 12 weeks or older and can be applied directly to their skin; it's the perfect flea spray for carpet and furniture as it will not leave any stains or residue
- FLEA & TICK FIGHTER: Say goodbye to fleas, larvae, eggs, ticks, and mosquitoes with our natural flea and tick spray. It eliminates existing infestations and helps protect against future pests—keeping your dog and home safe and comfortable.
- CERTIFIED NATURAL: Our flea & tick spray for dogs uses certified natural plant-based ingredients like peppermint oil and eugenol, keeping your dog safe from harsh chemicals; this flea spray leaves a pleasant scent that will have your dog feeling refreshed
$15.48
4

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Our rankings are cleverly generated from the algorithmic analysis of thousands of customer reviews about products, brands, merchant’s customer service level, popularity, trends and more. The rankings reflect our opinion and should be a good starting point for shopping.

Vet's Best

Vet’s Best Flea & Tick Home Spray for Dogs – Plant-Based Flea and Tick Treatment with Cotton Spice Scent – Indoor Flea Spray for Dogs – Made in USA Flea Control for Home Use – 32 oz

Vet's Best

$15.48

More Details
Main highlights
- SAFE AND WORRY FREE – Safe for your dog’s and home when used as directed.
- SAFE & EFFECTIVE FLEA & TICK CONTROL: Protect your dog and home with a formula safe for dogs and effective on pet bedding, carpets, floors, rugs, and drapes—helping keep your entire living space clear from pests. Gentle scent, powerful defense.
- PLANT-POWERED FORMULA: Vet’s Best Indoor Flea & Tick Home Spray uses a natural blend of certified essential oils to kill fleas, ticks, mosquitoes, spiders, ants, and bed bugs. Safe for use around dogs & the home—offering powerful, plant-based protection.
- COTTON SPICE SCENT: Infused with natural cottonseed and clove oils, this plant-based flea and tick spray leaves behind a cozy cotton spice aroma while effectively repelling pests—perfect for keeping your home smelling fresh and feeling protected.
- 30 YEARS OF TRUST: For more than three decades, Vet’s Best has delivered effective, plant-based solutions designed to protect, comfort, and soothe pets—earning the trust of pet owners who value natural care and lasting results.
- #1 NATURAL FLEA & TICK BRAND*: Trusted by pet parents, this cotton spice spray uses nature-derived ingredients like clove and cottonseed oil to kill fleas and ticks by contact, offering powerful yet gentle pest control. *Based on 2024 Nielsen Data.
$15.48
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Our rankings are cleverly generated from the algorithmic analysis of thousands of customer reviews about products, brands, merchant’s customer service level, popularity, trends and more. The rankings reflect our opinion and should be a good starting point for shopping.

Advantage

Advantage Dog Flea Treatment Spray | Kills Fleas & Ticks | Dog Flea Spray | 8 oz.

Advantage

$14.48

More Details
Main highlights
- Use as part of a complete dog flea treatment program - killing pests on your pets and in your home and yard with Advantage products
- Kills preadult fleas and flea eggs to prevent them from growing and becoming capable of biting
- Effective flea spray for dogs over 6 months old
- Delivers a whisper-quiet, continuous spray to provide 360-degree coverage while reducing stress to your dog
- Advantage Treatment Spray is a dog flea and tick treatment that kills and repels fleas, ticks and lice
$14.48

Best flea sprays for dogs - Holiday Sale 2025

K9 Advantix II Large Dog Vet-Recommended Flea, Tick & Mosquito Treatment & Prevention | Dogs 21 - 55 lbs. | 4-Mo Supply

Wondercide - Flea, Tick & Mosquito Spray for Dogs, Cats, and Home - Control, Prevention, Treatment - with Natural Essential Oils - Pet and Family Safe - Peppermint 16 oz

Vet’s Best Indoor Flea and Tick Spray – Dog Flea and Tick Treatment for Home, Plant-Based Formula with Natural Oils, Kills Fleas, Eggs & Ticks on Contact, Made in USA, 32 oz

Vet’s Best Flea & Tick Home Spray for Dogs – Plant-Based Flea and Tick Treatment with Cotton Spice Scent – Indoor Flea Spray for Dogs – Made in USA Flea Control for Home Use – 32 oz

Advantage Dog Flea Treatment Spray | Kills Fleas & Ticks | Dog Flea Spray | 8 oz.

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