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Best dog flea treatment that works - Holiday Sale 2025

Last Updated - December 14, 2025

1
Best Choice

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Our rankings are cleverly generated from the algorithmic analysis of thousands of customer reviews about products, brands, merchant’s customer service level, popularity, trends and more. The rankings reflect our opinion and should be a good starting point for shopping.

Capstar

Capstar for Dogs (nitenpyram), Fast-Acting Oral Flea Treatment for Dogs Over 25+ lbs, Vet-Recommended Flea Medication Tablets Start Killing in 30 Minutes, 6 Doses

Capstar

$39.97

More Details
Main highlights
- Treat Reinfestations Fast: If your pet gets reinfested with fleas, simply give another dose of this dog flea treatment as often as once a day
- Tackle Flea Infestations Fast: With one dose of CAPSTAR flea treatment, you can watch the dead fleas fall off your pet
- No Prescription Needed: Fast, effective flea treatment at home with nitenpyram for dogs that's available over the counter
- Intended Use: CAPSTAR Oral flea tablets for dogs (57 mg) is safe for puppies 4 weeks and older that weigh 25.1-125 pounds
- Fast-Acting Flea Treatment: CAPSTAR (nitenpyram) oral flea medicine for dogs starts killing adult fleas in just 30 minutes
$39.97
2

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Our rankings are cleverly generated from the algorithmic analysis of thousands of customer reviews about products, brands, merchant’s customer service level, popularity, trends and more. The rankings reflect our opinion and should be a good starting point for shopping.

Capstar

Capstar (Nitenpyram) Fast-Acting Oral Flea Treatment for Dogs 2-25 Lbs, Vet-Recommended Medication Tablets, Flea Tablets for Dogs Start Killing in 30 Minutes, 6 Doses

Capstar

$39.97

More Details
Main highlights
- Treat Reinfestations Fast: If your pet gets reinfested with fleas, simply give another dose of this flea treatment for dogs 2 to 25 lbs as often as once a day
- Tackle Flea Infestations Fast: With one dose of CAPSTAR flea medicine for dogs, you can watch the dead fleas fall off your pet
- No Prescription Needed: Fast, effective dog flea treatment that's available over the counter
- Intended Use: CAPSTAR for small dogs (57 mg) is safe for dogs and puppies 4 weeks and older that weigh 2-25 pounds
- Fast-Acting Dog Flea Medicine: CAPSTAR (nitenpyram for dogs) starts killing adult fleas in just 30 minutes
$39.97
3

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Our rankings are cleverly generated from the algorithmic analysis of thousands of customer reviews about products, brands, merchant’s customer service level, popularity, trends and more. The rankings reflect our opinion and should be a good starting point for shopping.

PetArmor

PetArmor CAPACTION (nitenpyram) Oral Flea Treatment for Dogs, Fast Acting Tablets Start Killing Fleas in 30 Minutes, Dogs Over 25 lbs, 6 Doses

PetArmor

$27.99

More Details
Main highlights
- TREAT RE-INFESTATIONS FAST: If your pet gets re-invested with fleas simply apply another dose as often as once a day. CapAction Flea Pills are even safe for use on pregnant or breeding dogs.
- SAFE TO USE: This oral flea medication is safe for puppies, dogs, cats, and kittens from 25lbs. and over, when used as directed.
- KILL FLEAS EFFICIENTLY: CapAction flea treatment has 6 doses and kills adult fleas that may cause allergy dermatitis.
- FAST-ACTING: One oral flea tablet starts killing fleas within 30 minutes of administration.
- EASY TO USE: Without the mess and rubbing off of a flea and tick topical treatment and without the need of a veterinarian prescription this dog flea tablet is administered orally to kill adult fleas fast.
$27.99
4
22% Off

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Our rankings are cleverly generated from the algorithmic analysis of thousands of customer reviews about products, brands, merchant’s customer service level, popularity, trends and more. The rankings reflect our opinion and should be a good starting point for shopping.

Frontline
22% Off

FRONTLINE Plus Flea and Tick Treatment for Large Dogs Up to 45 to 88 lbs. 3 Treatments

Frontline

$34.98

$44.99
(22% Off)

More Details
Main highlights
- Trusted by pet owners for over 20 years, FRONTLINE Plus for Dogs can be used on puppies as young as eight weeks old, weighing 5 pounds or more, and is easy to apply with one monthly dose providing protection from fleas & ticks for a full 30 days
- Treat all dogs or cats in your household monthly to effectively control fleas and ticks and prevent the establishment of new flea infestations
- Subscribe & save today to make it easier to keep your dogs or cats protected year-round and make sure you never run out of FRONTLINE Plus
- Subscribe & save today to make it easier to keep your dogs or cats protected year-round and make sure you never run out of FRONTLINE Plus
- Keep your dog protected from fleas & ticks all month long with FRONTLINE Plus for Dogs a fast-acting, waterproof flea & tick topical that's proven to kill fleas, flea eggs, flea larvae, chewing lice, and ticks that can transmit Lyme disease
- FRONTLINE Plus also comes in a formula designed for cats and kittens eight weeks of age and older, 1.5lbs. and over, so you can protect the dogs or cats in your house from fleas and ticks with FRONTLINE Brand Products
- Break the flea life cycle with FRONTLINE Plus, specially formulated with fipronil and (S)-methoprene to kill existing adult fleas, flea eggs and flea larvae to guard against further infestations for flea control
$34.98
$44.99 (22% Off)
5
Best Value
41% Off

✖
Our rankings are cleverly generated from the algorithmic analysis of thousands of customer reviews about products, brands, merchant’s customer service level, popularity, trends and more. The rankings reflect our opinion and should be a good starting point for shopping.

PetArmor
41% Off

PetArmor Plus Flea and Tick Prevention for Dogs, Large Dog Flea and Tick Treatment, 6 Doses, Waterproof Topical, Fast Acting (45-88 lbs)

PetArmor

$26.12

$44.99
(41% Off)

More Details
Main highlights
- Trusted, Vet Quality* Formula: This large dog flea and tick treatment contains fipronil and (S)-methoprene, the same active ingredients as FRONTLINE Plus for Dogs; PetArmor Plus for Dogs has a powerful formula that starts to kill fleas in 24 hours
- Fast Acting Long-Lasting Dog Flea & Tick Control: One application of PetArmor Plus lasts up to 30 days providing nose to tail protection. A 6-dose package lasts six months
- Effective, Waterproof Flea Treatment for Dogs: PetArmor Plus is a waterproof flea and tick treatment for dogs that kills fleas, eggs, larvae, ticks, and chewing lice up to 30 days after application
- Easy-to-use, Long-Lasting: PetArmor Plus tick and flea prevention for dogs comes with six (6) waterproof topical applications that provide your pet flea protection and control for six (6) months
- Break the Flea Cycle: Unlike other dog flea and tick prevention that may temporarily suppress flea activity, PETARMOR Plus Dog Flea Treatment works by effectively breaking the flea life cycle! Kill flea eggs and larvae to prevent re-infestation
$26.12
$44.99 (41% Off)

Best dog flea treatment that works - Holiday Sale 2025

Capstar for Dogs (nitenpyram), Fast-Acting Oral Flea Treatment for Dogs Over 25+ lbs, Vet-Recommended Flea Medication Tablets Start Killing in 30 Minutes, 6 Doses

Capstar (Nitenpyram) Fast-Acting Oral Flea Treatment for Dogs 2-25 Lbs, Vet-Recommended Medication Tablets, Flea Tablets for Dogs Start Killing in 30 Minutes, 6 Doses

PetArmor CAPACTION (nitenpyram) Oral Flea Treatment for Dogs, Fast Acting Tablets Start Killing Fleas in 30 Minutes, Dogs Over 25 lbs, 6 Doses

FRONTLINE Plus Flea and Tick Treatment for Large Dogs Up to 45 to 88 lbs. 3 Treatments

PetArmor Plus Flea and Tick Prevention for Dogs, Large Dog Flea and Tick Treatment, 6 Doses, Waterproof Topical, Fast Acting (45-88 lbs)

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