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Best systane eye drops for dry eyes - Holiday Sale 2025

Last Updated - December 14, 2025

1
Best Choice

✖
Our rankings are cleverly generated from the algorithmic analysis of thousands of customer reviews about products, brands, merchant’s customer service level, popularity, trends and more. The rankings reflect our opinion and should be a good starting point for shopping.

Systane

Systane Ultra Lubricant Eye Drops, 60 Count (Pack of 1), (Packaging may vary)

Systane

$27.26

$28.99
(5% Off)

More Details
Main highlights
- Single-Use Convenience. Store at room temperature
- Reduces both the signs and symptoms of dry eye
- Fast Long-Lasting Dry Eye Symptom Relief
- Extended Protection
- #1 Dr Recommended Brand of Artificial Tears*
$27.26
$28.99 (5% Off)
2
Best Value
27% Off

✖
Our rankings are cleverly generated from the algorithmic analysis of thousands of customer reviews about products, brands, merchant’s customer service level, popularity, trends and more. The rankings reflect our opinion and should be a good starting point for shopping.

Systane
27% Off

Systane PRO PF Multi-dose Preservative-Free Lubricant Eye Drops 2 Count

Systane

$21.89

$29.99
(27% Off)

More Details
Main highlights
- Trusted Brand: Systane is a trusted name in eye care, recommended by eye care professionals for its effective and reliable relief
- Triple-Action Dry Eye Relief: Systane Pro Preservative Free Eye Drops hydrate, restore and protect dry eyes for up to 12 hours of relief
- Tear Evaporation Protection: This unique formula helps lock in moisture and reduce tear evaporation
- Preservative-Free Formula: The gentle, preservative-free formula is ideal for sensitive eyes
- Long-Lasting Hydration: Systane Pro Preservative Free lubricating eye drops are formulated to support extended hydration for all types of dry eye relief
- Convenient Size: The 10mL bottle is perfect for daily use, offering you triple action dry eye relief at your fingertips
- Contact Lens Friendly*: safe for use with soft contact lenses
$21.89
$29.99 (27% Off)
3
25% Off

✖
Our rankings are cleverly generated from the algorithmic analysis of thousands of customer reviews about products, brands, merchant’s customer service level, popularity, trends and more. The rankings reflect our opinion and should be a good starting point for shopping.

Systane
25% Off

Systane Ultra Lubricant Eye Drops, Artificial Tears for Dry Eye, Twin Pack, 10-mL Each

Systane

$18.99

$25.49
(25% Off)

More Details
Main highlights
- Reduces both the signs and symptoms of dry eye
- Quickly soothe irritated eyes wherever you are
- Fast Long-Lasting Dry Eye Symptom Relief.Store at room temperature
- Extended Protection
- #1 Dr Recommended Brand of Artificial Tears*, packaging may vary
$18.99
$25.49 (25% Off)
4
18% Off

✖
Our rankings are cleverly generated from the algorithmic analysis of thousands of customer reviews about products, brands, merchant’s customer service level, popularity, trends and more. The rankings reflect our opinion and should be a good starting point for shopping.

Systane
18% Off

Systane Complete Lubricant Eye Drops, 0.34 Fl Oz, Twin Pack (Pack of 2)

Systane

$18.79

$22.99
(18% Off)

More Details
Main highlights
- Soothes eyes with fast-acting hydration
- Packaging may vary
- Optimal dry eye relief
- Nano-droplet technology takes our coverage to another level
- Hydrates fast and provides long-lasting relief
- Doctor Recommended Brand for Artifical Tears
$18.79
$22.99 (18% Off)
5

✖
Our rankings are cleverly generated from the algorithmic analysis of thousands of customer reviews about products, brands, merchant’s customer service level, popularity, trends and more. The rankings reflect our opinion and should be a good starting point for shopping.

Systane

Systane COMPLETE PF Multi-Dose Preservative Free Dry Eye Drops 0.34 Fl Oz, 2 count (pack of 1) (Packaging may vary)

Systane

$19.69

$20.97
(6% Off)

More Details
Main highlights
- Systane COMPLETE PF Eye Drops contains two 10mL bottles to use as needed to relieve, protect, and to lubricate dry eyes
- Safe for Use with Contact Lenses: Systane eye drops are safe for use with soft contact lenses
- Preservative-Free Eye Drop Solution: Ideal for users with sensitive eyes providing fast hydration and tear evaporation protection
- Nano-droplet technology features delivery of the eye drop over the entire eye surface for fast dry eye relief
- Long-Lasting Relief: Systane Complete PF eye drops help aqueous deficient, evaporative/lipid deficient dry eye
- 8 Hours of Dry Eye Relief: From doctor's reccomended #1 Brand
$19.69
$20.97 (6% Off)

Best systane eye drops for dry eyes - Holiday Sale 2025

Systane Ultra Lubricant Eye Drops, 60 Count (Pack of 1), (Packaging may vary)

Systane PRO PF Multi-dose Preservative-Free Lubricant Eye Drops 2 Count

Systane Ultra Lubricant Eye Drops, Artificial Tears for Dry Eye, Twin Pack, 10-mL Each

Systane Complete Lubricant Eye Drops, 0.34 Fl Oz, Twin Pack (Pack of 2)

Systane COMPLETE PF Multi-Dose Preservative Free Dry Eye Drops 0.34 Fl Oz, 2 count (pack of 1) (Packaging may vary)

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