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Best oral pain reliefs - Holiday Sale 2025

Last Updated - December 14, 2025

1
Best Choice

✖
Our rankings are cleverly generated from the algorithmic analysis of thousands of customer reviews about products, brands, merchant’s customer service level, popularity, trends and more. The rankings reflect our opinion and should be a good starting point for shopping.

Safetec

Oral Pain Relief, 0.75 Gram Packets (Box of 144)

Safetec

$24.84

More Details
Main highlights
$24.84
2

✖
Our rankings are cleverly generated from the algorithmic analysis of thousands of customer reviews about products, brands, merchant’s customer service level, popularity, trends and more. The rankings reflect our opinion and should be a good starting point for shopping.

Safetec

Safetec Oral Pain Relief, .75 g Packets, Box of 144

Safetec

$18.87

More Details
Main highlights
- Multi-colored
- 144 sealed packets of pain-relieving gel per box
- 0.75 gram packets
$18.87
3
25% Off

✖
Our rankings are cleverly generated from the algorithmic analysis of thousands of customer reviews about products, brands, merchant’s customer service level, popularity, trends and more. The rankings reflect our opinion and should be a good starting point for shopping.

Orajel
25% Off

Orajel 4X for Toothache & Gum Pain: Severe Cream Tube 0.33oz- From Oral Pain Relief Brand

Orajel

$7.48

$9.99
(25% Off)

More Details
Main highlights
- KILLS HARMFUL BACTERIA: Unique formula is designed to help kill harmful bacteria in the mouth, and can help to prevent infections
- INSTANT PAIN RELIEF: Instant pain relief with Orajel’s unique 4X clinical strength formula to help relieve pain of the tooth and gums
- EASY OPEN: Now with a Ready-Open Tube Tip for easy access to the relief you need. A convenient remedy for use at home or on the go.
- COOLING RELIEF: To help relieve gum irritation, Orajel 4X cream contains cooling relief
- 4X ACTIVE INGREDIENTS: With 4 active ingredients, Orajel Cream provides fast acting and maximum strength relief when you need it most
$7.48
$9.99 (25% Off)
4
Best Value
27% Off

✖
Our rankings are cleverly generated from the algorithmic analysis of thousands of customer reviews about products, brands, merchant’s customer service level, popularity, trends and more. The rankings reflect our opinion and should be a good starting point for shopping.

Orajel
27% Off

Orajel 4X for Toothache & Gum Pain Severe Gel Tube, No Color, 0.25 Ounce

Orajel

$7.25

$9.99
(27% Off)

More Details
Main highlights
- Proven to Kill Harmful Bacteria
- Now with a Ready-Open Tube Tip for easy access #1 Oral Pain Reliever Brand for Toothache
- Helps Prevent Infection
- Cooling Relief for Gum Irritation
- Clinical Strength Pain Relief
$7.25
$9.99 (27% Off)
5

✖
Our rankings are cleverly generated from the algorithmic analysis of thousands of customer reviews about products, brands, merchant’s customer service level, popularity, trends and more. The rankings reflect our opinion and should be a good starting point for shopping.

Orajel

Orajel Maximum Strength Nighttime Toothache Pain Relief Cream - 0.25 Oz

Orajel

$7.48

$8.28
(9% Off)

More Details
Main highlights
- B00433JHW2
$7.48
$8.28 (9% Off)

Best oral pain reliefs - Holiday Sale 2025

Oral Pain Relief, 0.75 Gram Packets (Box of 144)

Safetec Oral Pain Relief, .75 g Packets, Box of 144

Orajel 4X for Toothache & Gum Pain: Severe Cream Tube 0.33oz- From Oral Pain Relief Brand

Orajel 4X for Toothache & Gum Pain Severe Gel Tube, No Color, 0.25 Ounce

Orajel Maximum Strength Nighttime Toothache Pain Relief Cream - 0.25 Oz

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