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Best mitochondrial supplements - Holiday Sale 2025

Last Updated - December 14, 2025

1
Best Choice

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Our rankings are cleverly generated from the algorithmic analysis of thousands of customer reviews about products, brands, merchant’s customer service level, popularity, trends and more. The rankings reflect our opinion and should be a good starting point for shopping.

Timeline

Timeline Mitopure Urolithin A Supplement Softgels - Clinically Proven Support for Healthy Aging and Cellular Renewal - Mitoceutical for Muscle Support and Longevity

Timeline

$125.00

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Main highlights
- THE FOUNDATION OF HEALTHY AGING: Cellular energy powers every organ and system in the body. With consistent daily use, research shows improvements in cellular energy, muscle strength and cellular renewal in four months, with ongoing benefits building over time.
- PURE & PATENTED UROLITHIN A: Timeline’s breakthrough longevity supplement is powered by Mitopure, a proprietary, clinically validated form of Urolithin A that optimizes cellular health to target signs of aging at the source.
- MADE IN THE USA — TESTED FOR PURITY & POTENCY: Mitopure Softgels are vegan, non-GMO, NSF Certified for Sport, Clean Label Project Verified, and made in the USA using globally sourced ingredients. Every batch undergoes rigorous third-party testing for purity, safety and potency.
- CLINICALLY PROVEN BENEFITS FOR CELLULAR ENERGY & MUSCLE HEALTH: Mitopure is supported by 15+ years of longevity research and innovation, 50+ global patents and 5+ gold-standard clinical trials. One study showed that sedentary, middle-aged adults with an average BMI of 29.52 increased hamstring muscle strength by up to 12%.
- 6X MORE POWERFUL THAN DIET ALONE: Two softgels (500mg) deliver 6X more Urolithin A than a glass of 100% pure pomegranate juice, ensuring you get a clinically effective amount without having to rely on diet.*
$125.00
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22% Off

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Our rankings are cleverly generated from the algorithmic analysis of thousands of customer reviews about products, brands, merchant’s customer service level, popularity, trends and more. The rankings reflect our opinion and should be a good starting point for shopping.

Ortho Molecular Products
22% Off

Ortho Molecular Products Mitocore – 120 Capsules

Ortho Molecular Products

$92.50

$119.00
(22% Off)

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Main highlights
- Supports Immune Function
- Supports Detoxification Capacity
- Recharges Cellular Energy Production
- Increases Antioxidant Protection
$92.50
$119.00 (22% Off)
3
Best Value
32% Off

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Our rankings are cleverly generated from the algorithmic analysis of thousands of customer reviews about products, brands, merchant’s customer service level, popularity, trends and more. The rankings reflect our opinion and should be a good starting point for shopping.

Life Extension
32% Off

Life Extension Mitochondrial Energy Optimizer with PQQ - Energy Supplement for Healthy Mitochondria - With Taurine, Vitamin B, Pyrroloquinoline Quinone - Gluten-Free, Non-GMO - 120 Vegetarian Capsules

Life Extension

$43.88

$65.00
(32% Off)

More Details
Main highlights
- Supercharge your cellular energy—Mitochondria are the power suppliers of every cell in your body! Encourage the healthy function of mitochondria—and promote the creation of new mitochondria—with this PQQ supplement, which combines pyrroloquinoline quinone with carnosine, R-lipoic acid, taurine, vitamin B6 and benfotiamine to help power up your cellular energy production.
- Stay youthful, inside and out—The term “glycation” describes the physiological effects of getting older, which can make you feel and look beyond your years. Our formula includes carnosine, benfotiamine and vitamins B1 and B6 to inhibit the effects of glycation—including signs of aging, like wrinkled skin.
- Product Note: Exposure to heat or sunlight may lead to melting/damage of product. Hence customers are expected to be available during the product delivery.
- Live your healthiest life—For over 40 years, we’ve been developing advanced, effective formulas made with the highest standards and based on the latest scientific findings. We believe the answers to a healthier, richer life are within reach, and that rigorous scientific research is the path to get us there. That’s why so many of our nutritional formulas are designed using specific ingredients and amounts based on scientific studies.
- Ingredients matter—Sourced using only the finest raw ingredients with the purity and potency your body deserves. The majority of our products are non-GMO, gluten-free and manufactured in the USA—and a Certificate of Analysis is available for every product we produce.
- Help protect your cells—The amino acid taurine is in almost every cell of your body, and it helps inhibit inflammation to support cellular health as well as supporting those energy-generating mitochondria. Taurine isn’t the only defender in this energy supplement. PQQ and the R-form of alpha-lipoic acid help protect mitochondria from everyday oxidative stress and help keep them functioning like they did in younger years.
$43.88
$65.00 (32% Off)
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Our rankings are cleverly generated from the algorithmic analysis of thousands of customer reviews about products, brands, merchant’s customer service level, popularity, trends and more. The rankings reflect our opinion and should be a good starting point for shopping.

Resciency

Resciency 2326 MG Mitochondrial Supplements with ATP, Vitamins, CoQ10 & PQQ, More Effective Than Creatine HMB & Nitric Oxide, Energy, Endurance, Strength, Recovery & Muscle, Organic, 240 Capsules

Resciency

$39.99

More Details
Main highlights
- Superior Energy & Muscle: Reduce lethargy and fatigue while enhancing overall energy levels. Our blend of Coenzyme Q10, PQQ, Alpha-Lipoic Acid, and Acetyl-L-Carnitine HCl optimizes cellular energy, for mitochondrial function, and promotes new mitochondria growth. Increase endurance and muscle function. Ideal for busy individuals seeking a powerful supplement to performance and productivity
- Quality & Safety Assurance: Developed in partnership with experts. Manufactured in the USA in a GMP facility, it is free from contaminants and synthetic additives. If you have any questions or encounter any issues with our supplement, contact us—our dedicated team ensures quick refunds and efficient issue resolution
- Organic Ingredients: Our mitochondrial supplements include organic beetroot and maca root powders, providing natural energy and muscle performance. These pure, high-quality ingredients support overall well-being without synthetic additives or preservatives
- High Absorption & Antioxidant Protection: Our advanced formula includes Black Pepper Extract (95% Piperine) to ensure maximum nutrient absorption. Combined with Trans-Resveratrol and Turmeric Extract (95% Curcuminoids), it provides robust antioxidant protection. This reduces oxidative stress, speeds up recovery, and enhances endurance during workouts
- 2326 MG Extra Strength Formula: Do you know? Mitochondria are known as the powerhouses of the cells, producing about 90% of the energy your body needs. Unlike Creatine HMB & Nitric Oxide, our mitochondrial supplement combines their benefits and includes ATP, CoQ10, PQQ, vitamins, Alpha-Lipoic Acid, Acetyl-L-Carnitine HCl, and over 16 other ingredients for a more effective and comprehensive energy support*
$39.99
5

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Our rankings are cleverly generated from the algorithmic analysis of thousands of customer reviews about products, brands, merchant’s customer service level, popularity, trends and more. The rankings reflect our opinion and should be a good starting point for shopping.

Designs for Health

Designs for Health Mitochondrial NRG - Support Cellular Vitality + Metabolism - Mitochondria Energy Supplement with Alpha Lipoic Acid, Trans Resveratrol + Curcumin Powder (120 Vegan Capsules)

Designs for Health

$81.00

More Details
Main highlights
- Promote Optimum Performance - The formula supports those wanting to promote energy output for improved athletic performance, and anyone wishing to improve overall cellular and tissue health.*
- Patented Creatine - A unique for of creatine was added to support additional energy production. Patented Creatine MagnaPower supplies creatine and magnesium together, both needed for healthy mitochondrial function.*
- Energy (ATP) Production Support - A blend of nutrients, nutraceuticals, botanicals, and Krebs cycle intermediates designed to support efficient mitochondrial metabolism and energy production. Featuring active B vitamins, naturally fermented CoQ10, and ALA.*
- Clinically-Trusted Care - DFH is the #1 practitioner supplement brand recommended by functional medicine professionals and the #1 practitioner supplement brand personally trusted by functional medicine professionals.**
- Always Pure & Effective Products - This product is Vegetarian-Friendly, Non-GMO, and contains No Gluten, Dairy, or Soy*
$81.00

Best mitochondrial supplements - Holiday Sale 2025

Timeline Mitopure Urolithin A Supplement Softgels - Clinically Proven Support for Healthy Aging and Cellular Renewal - Mitoceutical for Muscle Support and Longevity

Ortho Molecular Products Mitocore – 120 Capsules

Life Extension Mitochondrial Energy Optimizer with PQQ - Energy Supplement for Healthy Mitochondria - With Taurine, Vitamin B, Pyrroloquinoline Quinone - Gluten-Free, Non-GMO - 120 Vegetarian Capsules

Resciency 2326 MG Mitochondrial Supplements with ATP, Vitamins, CoQ10 & PQQ, More Effective Than Creatine HMB & Nitric Oxide, Energy, Endurance, Strength, Recovery & Muscle, Organic, 240 Capsules

Designs for Health Mitochondrial NRG - Support Cellular Vitality + Metabolism - Mitochondria Energy Supplement with Alpha Lipoic Acid, Trans Resveratrol + Curcumin Powder (120 Vegan Capsules)

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