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Best lubricating eye drops - Holiday Sale 2025

Last Updated - December 14, 2025

1
Best Choice
40% Off

✖
Our rankings are cleverly generated from the algorithmic analysis of thousands of customer reviews about products, brands, merchant’s customer service level, popularity, trends and more. The rankings reflect our opinion and should be a good starting point for shopping.

Refresh
40% Off

Refresh Optive MEGA-3 Lubricant Eye Drops Preservative-Free Artificial Tears, 0.01 fl oz (0.4 mL), 60 Single-Use Containers

Refresh

$23.86

$39.99
(40% Off)

More Details
Main highlights
- TRUSTED: From the #1 doctor-recommended preservative-free brand with over 35 years of experience (Data on file, AbbVie, Inc. REF113774)
- TRIPLE-ACTION FORMULA: Lubricates, hydrates, and protects tears from evaporating
- PRESERVATIVE-FREE: Enhanced with antioxidants and plant-based Flaxseed Oil (inactive ingredients) which contains omega-3s
- ON-THE-GO VIALS: 60 sterile single-use vials per carton that are easy and safe to use as often as needed
- LASTING RELIEF: Soothes and prevents further irritation
- FSA & HSA ELIGIBLE: Your pre-tax dollars may cover this product as an out-of-pocket expense depending on your plan
- FAST-ACTING: Rapid relief to comfort dry, irritated eyes
- ADVANCED HYDRATION: Innovated with patented HydroCell technology that enables rehydration
$23.86
$39.99 (40% Off)
2
20% Off

✖
Our rankings are cleverly generated from the algorithmic analysis of thousands of customer reviews about products, brands, merchant’s customer service level, popularity, trends and more. The rankings reflect our opinion and should be a good starting point for shopping.

Systane
20% Off

Systane Ultra Lubricant Eye Drops, 60 Count (Pack of 1), (Packaging may vary)

Systane

$22.99

$28.99
(20% Off)

More Details
Main highlights
- Single-Use Convenience. Store at room temperature
- Reduces both the signs and symptoms of dry eye
- Fast Long-Lasting Dry Eye Symptom Relief
- Extended Protection
- #1 Dr Recommended Brand of Artificial Tears*
$22.99
$28.99 (20% Off)
3
15% Off

✖
Our rankings are cleverly generated from the algorithmic analysis of thousands of customer reviews about products, brands, merchant’s customer service level, popularity, trends and more. The rankings reflect our opinion and should be a good starting point for shopping.

Refresh
15% Off

Refresh Tears, Lubricant Eye Drops, 2 Bottles .5 fl oz (15 ml)

Refresh

$13.29

$15.75
(15% Off)

More Details
Main highlights
- PROTECTIVE MOISTURE BARRIER: Helps shield eyes from further dryness and irritation caused by environmental factors.
- MIMICS NATURAL TEARS: Formulated to closely resemble natural tears, providing soothing and effective hydration.
- IMMEDIATE DRY EYE RELIEF: Quickly alleviates dryness, irritation, and discomfort by replenishing moisture to the eyes.
- GENTLE DAILY FORMULA: Non-irritating and suitable for frequent use to maintain eye comfort throughout the day.
- CONTACT LENS COMPATIBLE: Safe for use with contact lenses, making it convenient for individuals with corrective eyewear.
$13.29
$15.75 (15% Off)
4
31% Off

✖
Our rankings are cleverly generated from the algorithmic analysis of thousands of customer reviews about products, brands, merchant’s customer service level, popularity, trends and more. The rankings reflect our opinion and should be a good starting point for shopping.

Systane
31% Off

Systane Ultra Lubricant Eye Drops, Artificial Tears for Dry Eye, Twin Pack, 10-mL Each

Systane

$17.36

$25.49
(31% Off)

More Details
Main highlights
- Reduces both the signs and symptoms of dry eye
- Quickly soothe irritated eyes wherever you are
- Fast Long-Lasting Dry Eye Symptom Relief.Store at room temperature
- Extended Protection
- #1 Dr Recommended Brand of Artificial Tears*, packaging may vary
$17.36
$25.49 (31% Off)
5
Best Value
38% Off

✖
Our rankings are cleverly generated from the algorithmic analysis of thousands of customer reviews about products, brands, merchant’s customer service level, popularity, trends and more. The rankings reflect our opinion and should be a good starting point for shopping.

TheraTears
38% Off

TheraTears Extra Dry Eye Drops, Twin Pack, 2 Bottles x 0.5 fl oz (Pack of 1)

TheraTears

$13.49

$21.99
(38% Off)

More Details
Main highlights
- Instant hydration: TheraTears EXTRA eye drops restore eyes’ natural balance and deliver fast hydration relief for dry eyes, because hydration supports dry eye health
- Immediate dry eye relief: TheraTears EXTRA Dry Eye Therapy lubricating eye drops provide immediate relief from dry eye symptoms; this formula delivers EXTRAordinary relief with up to 12 hours of hydrating comfort
- Electrolytes: TheraTears eye drops’ unique formula contains OxyLytes, the 5 vital electrolytes found in natural tears
- Doctor-recommended: TheraTears is a doctor-recommended brand (per ProVoice Survey data collected 9/1/23-8/31/24), created to bring balance and hydration to dry eyes; your purchase may be FSA/HSA eligible, check your health plan for details
- Created by an ophthalmologist: The TheraTears formula was created by an ophthalmologist, following 18 years of research, for a one-of-a-kind eye drop
$13.49
$21.99 (38% Off)

Best lubricating eye drops - Holiday Sale 2025

Refresh Optive MEGA-3 Lubricant Eye Drops Preservative-Free Artificial Tears, 0.01 fl oz (0.4 mL), 60 Single-Use Containers

Systane Ultra Lubricant Eye Drops, 60 Count (Pack of 1), (Packaging may vary)

Refresh Tears, Lubricant Eye Drops, 2 Bottles .5 fl oz (15 ml)

Systane Ultra Lubricant Eye Drops, Artificial Tears for Dry Eye, Twin Pack, 10-mL Each

TheraTears Extra Dry Eye Drops, Twin Pack, 2 Bottles x 0.5 fl oz (Pack of 1)

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Systane Ultra Lubricant Eye Drops,0.14 Fl Oz (Pack of 1)

TheraTears Dry Eye Therapy Eye Drops for Dry Eyes, 0.5 Fl Oz

Refresh Optive Lubricant Eye Drops For Dry Eyes, Preservative-Free, 0.01 Fl Oz Single-Use Containers, 60 Count

Systane COMPLETE PF Multi-Dose Preservative Free Dry Eye Drops 0.34 Fl Oz, 2 count (pack of 1) (Packaging may vary)

Refresh Liquigel Lubricant Eye Gel Drops, 0.5 Fl Oz Sterile

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