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Best lice treatments - Holiday Sale 2025

Last Updated - December 14, 2025

1
Best Choice

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Our rankings are cleverly generated from the algorithmic analysis of thousands of customer reviews about products, brands, merchant’s customer service level, popularity, trends and more. The rankings reflect our opinion and should be a good starting point for shopping.

TARO

Ivermectin Lotion 0.5% Lice Treatment (4 Fl Oz) Fast-Acting 10-Minute Single Use, Prescription Strength Solution for Head Lice & Eggs, No Nit Combing Required, Adults & Kids 6 Months+

TARO

$39.99

More Details
Main highlights
- Prescription-Strength Ivermectin: Utilizing ivermectin, this strongest lice treatment offers medical-grade effectiveness. It serves as a reliable lice and nit killer, ensuring comprehensive treatment in just one application.
- Other Information: Tamper Evident: Do not use if the tamper seal on the tube has been broken. Store at room temperature 68 degrees-77 degrees F (20 degrees-25 degrees C). Do not freeze. Keep carton and see consumer information leaflet and warnings before use. For single use. Discard the tube after use.
- One and Done Lice Treatment: Experience the convenience of our one and done lice treatment, crafted with prescription-strength ivermectin. This lice treatment lotion eliminates lice and nits in one application, eliminating the need for nit combing.
- No Nit Combing Required: Our lice treatment for adults offers a hassle-free solution with no nit combing required. This advanced lice medicine for hair is designed to effectively target and eliminate lice and their eggs, ensuring a clean and clear scalp.
- Lotion That Kills Eggs and Lice: Benefit from a lice treatment that kills eggs and lice with prescription-strength ivermectin. This head lice treatment lotion is ideal for the whole family, offering a reliable lice hair treatment without the need for repeated applications.
- Lice Hair Treatment: Formulated with extreme potency, this lice treatment for hair is among the best hair lice treatments available. It serves as an effective lice removal treatment, providing a reliable solution to kill lice and lice eggs efficiently.
$39.99
2

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Our rankings are cleverly generated from the algorithmic analysis of thousands of customer reviews about products, brands, merchant’s customer service level, popularity, trends and more. The rankings reflect our opinion and should be a good starting point for shopping.

MAYDAY

MAYDAY Daily Lice Routine Bundle – 12oz Shampoo & 12oz Conditioner | Non-Toxic, Pesticide-Free, Scientifically Proven Lice Defense for All Hair Types | Sandalwood & Mint Formula

MAYDAY

$37.99

More Details
Main highlights
- Scientifically Proven: Scientifically Proven and effective in eliminating lice and preventing re-infestation, providing long-lasting protection for the whole family.
- Non-Toxic & Chemical-Free: Free from harmful chemicals and pesticides, both products are made with natural ingredients like Sandalwood and Mint for safe lice protection.
- Hydrates & Nourishes: The shampoo cleans and protects while the conditioner helps detangle, hydrate, and leave hair soft, smooth, and lice-free.
- Family-Friendly: Safe for both children and adults, this bundle is ideal for daily lice defense and hair care, suitable for sensitive scalps.
- Complete Daily Lice Defense Routine: The Mayday Daily Lice Routine Bundle includes both 12oz Shampoo and 12oz Conditioner for a full lice prevention system.
$37.99
3
Best Value
14% Off

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Our rankings are cleverly generated from the algorithmic analysis of thousands of customer reviews about products, brands, merchant’s customer service level, popularity, trends and more. The rankings reflect our opinion and should be a good starting point for shopping.

RID
14% Off

RID One & Done, Just One Application Head Lice Treatment, No Combing Required, Prescription Strength Ivermectin Lotion for Children & Adults, Eliminates Super Lice & Renders Eggs Non Viable

RID

$29.99

$34.99
(14% Off)

More Details
Main highlights
- PRESCRIPTION STRENGTH: Powered by the original prescription strength ivermectin lotion 0.5%
- PEDIATRICIAN RECOMMENDED: The active ingredient in this head lice treatment is endorsed by the American Academy of Pediatrics for treating super lice, which are tougher-to-kill lice that have built a resistance to traditional permethrin/pyrethroid lice treatments over time
- ONE & DONE LICE TREATMENT: Effectively treats head lice, super lice & eggs (nits) with just 1 application — No second application needed
- NO NIT COMBING REQUIRED: Clinically proven without the hassle of combing out nits (eggs)
- CHILD-SAFE FORMULA: Approved for use on children 6 months and up
- 10 MINUTE TREATMENT: In just 10 minutes kills lice and leaves eggs (nits) non-viable
$29.99
$34.99 (14% Off)
4

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Our rankings are cleverly generated from the algorithmic analysis of thousands of customer reviews about products, brands, merchant’s customer service level, popularity, trends and more. The rankings reflect our opinion and should be a good starting point for shopping.

Nix

Nix Lice Treatment & Prevention Kit, All-in-One Shampoo, 4 fl oz, with Lice Removal Comb and Lice Prevention Daily Leave-in Spray, 6 fl oz

Nix

$28.98

More Details
Main highlights
- TREATS & CLEANS HAIR IN 10 MINUTES: The Nix Ultra All-in-One Shampoo gently treats and cleanses hair in only 10 minutes with a 1-step easy application, no additional shampoo required
- PESTICIDE-FREE TREAT & PREVENT KIT: The Nix Ultra Lice Treatment & Prevention Kit contains both the Nix Ultra All-in-One Shampoo that kills superlice, lice and eggs (also known as nits) and the Nix Lice Prevention Daily Leave-In Spray to keep your family protected from superlice & lice
- KILLS LICE WITHOUT COMBING: Includes Lice Removal Comb for convenience to assist in removing superlice, lice and eggs (nits) from hair after lice treatment
- DEFEND & REPEL SUPERLICE: The Nix Lice Prevention Daily Leave-In Spray defends and repels superlice & lice and provides long-lasting protection* to keep you and your family protected before, during and after treatment
- #1 PEDIATRICIAN RECOMMENDED BRAND*: Nix is the number one pediatrician-recommended lice removal brand that offers both treatment and prevention products; *Based on Pediatrician Survey December 31, 2024
$28.98
5

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Our rankings are cleverly generated from the algorithmic analysis of thousands of customer reviews about products, brands, merchant’s customer service level, popularity, trends and more. The rankings reflect our opinion and should be a good starting point for shopping.

RID

RID Super Max Lice Treatment Kit, Kills Lice & Super Lice & Eggs + 24/7 Lice Defense, Pesticide Free, 3.4 FL OZ Solution + 6.8 FL OZ Daily Defense Shampoo & Conditioner + Nit Removal Comb

RID

$24.98

More Details
Main highlights
- The advanced treatment solution is enhanced with lice defense ingredients to not only kill super lice and eggs but also to help keep new lice away from treated hair.
- The Only 5 in 1 Lice Complete Lice Treatment Kit: 1) Kills Lice Fast 2) Even Kills Hard-to-Kill Super Lice 3) Kills Eggs 4) Blocks New Lice 5) Plus provides ongoing 24/7 lice defense upon return to school or camp.
- Plus includes RID Daily Defense Shampoo & Conditioner to help keep lice away 24/7 upon return to school or camp (with daily use).
- No Harsh Chemicals & No Pesticides: It is tough on lice but gentle on kids.
- Kills Lice Better than the Leading Pesticide: Clinical testing shows that Rid Super Max is more effective at killing head lice than the leading pesticide ingredient.
- 100% effective at keeping lice away when Daily Defense Shampoo & Conditioner is used daily.
$24.98

Best lice treatments - Holiday Sale 2025

Ivermectin Lotion 0.5% Lice Treatment (4 Fl Oz) Fast-Acting 10-Minute Single Use, Prescription Strength Solution for Head Lice & Eggs, No Nit Combing Required, Adults & Kids 6 Months+

MAYDAY Daily Lice Routine Bundle – 12oz Shampoo & 12oz Conditioner | Non-Toxic, Pesticide-Free, Scientifically Proven Lice Defense for All Hair Types | Sandalwood & Mint Formula

RID One & Done, Just One Application Head Lice Treatment, No Combing Required, Prescription Strength Ivermectin Lotion for Children & Adults, Eliminates Super Lice & Renders Eggs Non Viable

Nix Lice Treatment & Prevention Kit, All-in-One Shampoo, 4 fl oz, with Lice Removal Comb and Lice Prevention Daily Leave-in Spray, 6 fl oz

RID Super Max Lice Treatment Kit, Kills Lice & Super Lice & Eggs + 24/7 Lice Defense, Pesticide Free, 3.4 FL OZ Solution + 6.8 FL OZ Daily Defense Shampoo & Conditioner + Nit Removal Comb

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