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Best kleenex original extra large tissues - April 2026

Last Updated - April 2, 2026

1
Best Choice

✖
Our rankings are cleverly generated from the algorithmic analysis of thousands of customer reviews about products, brands, merchant’s customer service level, popularity, trends and more. The rankings reflect our opinion and should be a good starting point for shopping.

Kleenex

Kleenex Professional Naturals Facial Tissue with Plastic-Free Eco Packaging, Bulk (56027), 2-Ply, White, Upright Cube Boxed Format, Designed for Business (90 Tissues/Box, 36 Boxes, 3,240 Sheets/Case)

Kleenex

$79.99

More Details
Main highlights
- The Signal Sheet keeps you ahead of run-outs (final 10 tissues are colored light blue instead of white, so you'll know it's time to replace the box)
- Kleenex is the #1 brand of facial tissue in North America and is trusted by more consumers than any other
- Kleenex Professional Naturals Facial Tissue is FSC certified; FSC mix paper supporting responsible forestry
- Each Kleenex tissue is 2-ply, absorbent, soft and strong; created with a blend of virgin fiber and recycled fiber; plastic-free carton featuring a paper baffle
- 90 Tissues/Box; 36 Boxes of Kleenex Naturals with Plastic Free Eco Packaging/Case; 3,240 Tissues/Case; 2-Ply; White; Upright Facial Tissue Cube Boxes for Business
$79.99
2

✖
Our rankings are cleverly generated from the algorithmic analysis of thousands of customer reviews about products, brands, merchant’s customer service level, popularity, trends and more. The rankings reflect our opinion and should be a good starting point for shopping.

Kleenex

Kleenex Professional Naturals Facial Tissue with Plastic-Free Eco Packaging, Bulk (56027), 2-Ply, White, Upright Cube Boxed Format, Designed for Business (90 Tissues/Box, 36 Boxes, 3,240 Sheets/Case)

Kleenex

$75.99

$79.99
(5% Off)

More Details
Main highlights
- The Signal Sheet keeps you ahead of run-outs (final 10 tissues are colored light blue instead of white, so you'll know it's time to replace the box)
- Kleenex is the #1 brand of facial tissue in North America and is trusted by more consumers than any other
- Kleenex Professional Naturals Facial Tissue is FSC certified; FSC mix paper supporting responsible forestry
- Each Kleenex tissue is 2-ply, absorbent, soft and strong; created with a blend of virgin fiber and recycled fiber; plastic-free carton featuring a paper baffle
- 90 Tissues/Box; 36 Boxes of Kleenex Naturals with Plastic Free Eco Packaging/Case; 3,240 Tissues/Case; 2-Ply; White; Upright Facial Tissue Cube Boxes for Business
$75.99
$79.99 (5% Off)
3

✖
Our rankings are cleverly generated from the algorithmic analysis of thousands of customer reviews about products, brands, merchant’s customer service level, popularity, trends and more. The rankings reflect our opinion and should be a good starting point for shopping.

Kleenex

Kleenex Ultra Soft Facial Tissues, 18 Flat Boxes, 120 Tissues per Box, 3-Ply (2,160 Total), Packaging May Vary

Kleenex

$35.64

$37.99
(6% Off)

More Details
Main highlights
- WHAT'S INCLUDED — 18 flat boxes of Kleenex Ultra Soft Facial Tissues, 3-Ply, 120 tissues per box (2,160 tissues total)
- THE #1 ULTRA TISSUE* — We’re the #1 ultra tissue* for a reason. Kleenex Ultra Soft comforts skin and helps protect hands with every tissue (*among national brands)
- SILKY SOFTNESS— These facial tissues are made with 3 layers of silky-soft strength that’s gentle on watery eyes and runny noses for an extra bit of comfort when you need it
- SAVE YOUR TOILET PAPER — When it comes to blowing your nose, Kleenex has got you covered. Our tissues are made with Clean Shield that contains the mess better than the leading value toilet paper
- FOR THE BIG AND LITTLE MOMENTS — Back to school season, allergy season, holiday season, graduation season, and every season in between, Kleenex Ultra Soft is there for it all
- ALLERGIST APPROVED — Our tissues are hypoallergenic, dermatologist tested, and allergist approved
$35.64
$37.99 (6% Off)
4
Best Value
16% Off

✖
Our rankings are cleverly generated from the algorithmic analysis of thousands of customer reviews about products, brands, merchant’s customer service level, popularity, trends and more. The rankings reflect our opinion and should be a good starting point for shopping.

Kleenex
16% Off

Kleenex Ultra Soft Facial Tissues, 18 Flat Boxes, 120 Tissues per Box, 3-Ply (2,160 Total), Packaging May Vary

Kleenex

$32.08

$37.99
(16% Off)

More Details
Main highlights
- WHAT'S INCLUDED — 18 flat boxes of Kleenex Ultra Soft Facial Tissues, 3-Ply, 120 tissues per box (2,160 tissues total)
- THE #1 ULTRA TISSUE* — We’re the #1 ultra tissue* for a reason. Kleenex Ultra Soft comforts skin and helps protect hands with every tissue (*among national brands)
- SILKY SOFTNESS— These facial tissues are made with 3 layers of silky-soft strength that’s gentle on watery eyes and runny noses for an extra bit of comfort when you need it
- SAVE YOUR TOILET PAPER — When it comes to blowing your nose, Kleenex has got you covered. Our tissues are made with Clean Shield that contains the mess better than the leading value toilet paper
- FOR THE BIG AND LITTLE MOMENTS — Back to school season, allergy season, holiday season, graduation season, and every season in between, Kleenex Ultra Soft is there for it all
- ALLERGIST APPROVED — Our tissues are hypoallergenic, dermatologist tested, and allergist approved
$32.08
$37.99 (16% Off)
5

✖
Our rankings are cleverly generated from the algorithmic analysis of thousands of customer reviews about products, brands, merchant’s customer service level, popularity, trends and more. The rankings reflect our opinion and should be a good starting point for shopping.

Kleenex

Kleenex Professional Facial Tissue, Bulk (21400), 2-Ply, White, Flat Boxed Format, Designed for Business (100 Tissues/Box, 36 Boxes, 3,600 Sheets/Case)

Kleenex

$60.96

More Details
Main highlights
- Kleenex is the #1 brand of facial tissue in North America, trusted by more consumers than any other
- FSC certified; FSC mix paper supporting responsible forestry
- Each tissue features smart innovations like an ultra-soft feel
- Each Kleenex tissue is 2-ply, absorbent, soft and strong
- 100 Tissues/Box; 36 Boxes of Kleenex Professional Facial Tissue/Case; 3,600 Tissues/Case; 2-Ply; White; Flat Facial Tissue Boxes for Business
$60.96

Best kleenex original extra large tissues - April 2026

Kleenex Professional Naturals Facial Tissue with Plastic-Free Eco Packaging, Bulk (56027), 2-Ply, White, Upright Cube Boxed Format, Designed for Business (90 Tissues/Box, 36 Boxes, 3,240 Sheets/Case)

Kleenex Professional Naturals Facial Tissue with Plastic-Free Eco Packaging, Bulk (56027), 2-Ply, White, Upright Cube Boxed Format, Designed for Business (90 Tissues/Box, 36 Boxes, 3,240 Sheets/Case)

Kleenex Ultra Soft Facial Tissues, 18 Flat Boxes, 120 Tissues per Box, 3-Ply (2,160 Total), Packaging May Vary

Kleenex Ultra Soft Facial Tissues, 18 Flat Boxes, 120 Tissues per Box, 3-Ply (2,160 Total), Packaging May Vary

Kleenex Professional Facial Tissue, Bulk (21400), 2-Ply, White, Flat Boxed Format, Designed for Business (100 Tissues/Box, 36 Boxes, 3,600 Sheets/Case)

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