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Best itching rash treatments - Holiday Sale 2025

Last Updated - December 14, 2025

1
Best Choice

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Our rankings are cleverly generated from the algorithmic analysis of thousands of customer reviews about products, brands, merchant’s customer service level, popularity, trends and more. The rankings reflect our opinion and should be a good starting point for shopping.

Cortizone 10

Cortizone-10 Maximum Strength Soothing Aloe Itch Relief Cream, 1% Hydrocortisone, Fast-Acting, Anti-Itch Cream for Bug Bites, Rash, Eczema, Psoriasis, Poison Ivy, Oak, Sumac, 2 oz (Pack of 4)

Cortizone 10

$35.88

More Details
Main highlights
- TRAVEL ESSENTIALS: The perfect addition to first aid kits, camping essentials and travel bags for anytime you need on-the-go relief
- RELIEVES ITCH: Cortizone-10 helps relieve itch associated with minor skin irritations, inflammation, and rashes due to eczema, psoriasis, insect bites, seborrheic dermatitis, poison ivy, oak, sumac, and more
- INCLUDES: Four (4) 2 oz. tubes of Cortizone-10 Maximum Strength* Soothing Aloe Itch Relief Cream (*Among topical anti-itch OTCs)
- FAST ACTING: Relieves itch in five minutes with a fragrance-free and dye-free formula
- DOCTOR RECOMMENDED: Cortizone-10 is the No. 1 doctor-recommended OTC anti-itch brand* and is suitable for adults and children ages 2+ (*2024 IQVIA Study)
- ACTIVE INGREDIENT: Formulated with 1% hydrocortisone for maximum-strength itch relief without a prescription
$35.88
2
Best Value
10% Off

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Our rankings are cleverly generated from the algorithmic analysis of thousands of customer reviews about products, brands, merchant’s customer service level, popularity, trends and more. The rankings reflect our opinion and should be a good starting point for shopping.

Dermeleve
10% Off

Dermeleve Steroid Free Anti-Itch Cream | Extra Strength for Psoriasis, Seborrheic Dermatitis, Viral Rash, Bug Bites, Allergy, Chronic Hives, Neuropathy (Nerve) | Full Body Itch Relief | 2 oz (1 Pack)

Dermeleve

$26.99

$29.99
(10% Off)

More Details
Main highlights
- STOPS 3 TYPES OF ITCH in minutes (1) Hard to treat chronic and senior itch that has lasted 6 weeks or more (2) Itch without a rash (3) Allergic itch, such as Hives, Insect Bites & Stings, and Contact Dermatitis.
- STEROID-FREE ANTI-ITCH CREAM: Dermeleve is a next-generation OTC itchy skin relief cream formulated specifically to deliver safe, maximum strength results—even for sensitive body parts, intimate areas, and thinning skin. Suitable for all unbroken skin, it provides effective, fast itch relief.
- SOOTHES DRY, IRRITATED SKIN with SrX-38, Ceramides, Hyaluronic Acid, and Vitamins C & E. Our non-steroid itchy skin lotion moisturizes and nourishes painful skin, promoting skin barrier repair and enhancing the skin's natural resilience against further irritation.
- NON-GREASY, REAPPLY AS NEEDED: This gentle, yet highly effective, anti-itch lotion absorbs quickly and won't make your skin greasy. Free of fragrances, corticosteroids, formaldehyde, parabens, and skin-clogging ingredients. Hypoallergenic, non-toxic and safe for non-broken skin of all types.
- DEVELOPED & TRUSTED BY DERMATOLOGISTS across the United States. Dermeleve anti-itch cream is manufactured by Advanced Derm Solutions, a science and solutions focused company based in Tampa, Florida.
$26.99
$29.99 (10% Off)
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Our rankings are cleverly generated from the algorithmic analysis of thousands of customer reviews about products, brands, merchant’s customer service level, popularity, trends and more. The rankings reflect our opinion and should be a good starting point for shopping.

Globe

Globe Hydrocortisone Maximum Strength Cream 1% w/Aloe, 16 oz, Anti-Itch Cream for Redness, Swelling, Itching, Rash, Bug/Mosquito Bites, Eczema, Hemorrhoids & More, 16 oz Jar

Globe

$15.99

More Details
Main highlights
- QUALITY: Manufactured in accordance with the highest pharmaceutical manufacturing processes and contains a NDC for 100% confidence. Trifecta Pharmaceuticals USA is a family business based in sunny Fort Lauderdale, Florida USA.
- PREMIUM QUALITY MANUFACTURING: Manufactured in USFDA-audited facilities, Globe products meet the highest pharmaceutical standards. Compare to leading name brand ingredients for cost-effective, reliable relief.
- PHARMACIST RECOMMENDED: Hydrocortisone is highly effective in easing symptoms of eczema, psoriasis, and dermatitis, particularly itching, redness, and discomfort. Safe to use for insect bites and rashes caused by poison ivy and oak, offering reliable alleviation from irritated skin.
- MAXIMUM STRENGTH FORMULA: Globe Hydrocortisone Cream 1% with Aloe combines powerful hydrocortisone with soothing aloe for rapid relief from itching, redness, and irritation. Ideal for eczema, psoriasis, insect bites, and more.
- FAST ITCH RELIEF: Provides fast relief from skin irritation, rashes, redness, and bug bites. Helps with poison ivy, oak, sumac, and other skin conditions. Perfect for easing symptoms of dermatitis and reducing swelling.
- ESSENTIAL FOR HOME & TRAVEL: Keep this hydrocortisone cream in your home, car, or travel kit. Cleanse the affected area with mild soap and apply up to 4 times daily for immediate alleviation from itching and redness.
$15.99
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Our rankings are cleverly generated from the algorithmic analysis of thousands of customer reviews about products, brands, merchant’s customer service level, popularity, trends and more. The rankings reflect our opinion and should be a good starting point for shopping.

Aquaphor

Aquaphor Itch Relief Ointment, Maximum Strength 1% Hydrocortisone, Relieves Itch from Skin Irritation, Insect Bites, Psoriasis, Skin Rashes, Eczema, & Poison Ivy, 2 oz

Aquaphor

$15.94

More Details
Main highlights
- Outdoor Irritation Relief: Clinically proven to help provide instant itch relief for outdoor irritations like insect bites, poison ivy, poison oak, and sumac
- Long Lasting Itch Relief: Aquaphor Itch Relief ointment soothes and relieves itch and irritation for up to 12 hours
- Indoor Itch Relief: This skin ointment can also help to soothe and relieve itchiness from indoor causes like dry skin, skin rash, and psoriasis
- Includes one (1) 2 ounce tube of Aquaphor Itch Relief Ointment
- Helps Heal the Itch: Formula features 1% hydrocortisone anti itch ointment, and is fragrance free, paraben free, and hypoallergenic
$15.94
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Our rankings are cleverly generated from the algorithmic analysis of thousands of customer reviews about products, brands, merchant’s customer service level, popularity, trends and more. The rankings reflect our opinion and should be a good starting point for shopping.

Lotrimin

Lotrimin Ultra Jock Itch Cream - Powerful Butenafine Hydrochloride Treatment for Jock Itch, 0.42 Ounce (12 Grams) (Packaging May Vary)

Lotrimin

$12.47

More Details
Main highlights
- Safe For Kids Over 12: Help your teenage athlete with the burning, chafing skin caused by jock itch on his or her inner thighs and crotch with this anti fungal cream
- Provides Soothing Itchy Skin Relief: Treat the discomfort of itchy skin on the groin and inner thighs with Lotrimin ultra-jock itch cream
- Proven to cure most jock itch: Clinically proven to cure most jock itch infections, Lotrimin Ultra Antifungal Cream kills the fungus that causes tinea cruris, commonly known as jock itch
- Ideal For Men and Women: Many people assume that only men get jock itch, but women are also prone to fungal infections on their crotch skin
- Formula: Lotrimin Ultra fungus cream contains butenafine hydrochloride to help kill the fungus that cause jock itch in your groin area. Store between 20° to 25°C (68° to 77°F)
$12.47

Best itching rash treatments - Holiday Sale 2025

Cortizone-10 Maximum Strength Soothing Aloe Itch Relief Cream, 1% Hydrocortisone, Fast-Acting, Anti-Itch Cream for Bug Bites, Rash, Eczema, Psoriasis, Poison Ivy, Oak, Sumac, 2 oz (Pack of 4)

Dermeleve Steroid Free Anti-Itch Cream | Extra Strength for Psoriasis, Seborrheic Dermatitis, Viral Rash, Bug Bites, Allergy, Chronic Hives, Neuropathy (Nerve) | Full Body Itch Relief | 2 oz (1 Pack)

Globe Hydrocortisone Maximum Strength Cream 1% w/Aloe, 16 oz, Anti-Itch Cream for Redness, Swelling, Itching, Rash, Bug/Mosquito Bites, Eczema, Hemorrhoids & More, 16 oz Jar

Aquaphor Itch Relief Ointment, Maximum Strength 1% Hydrocortisone, Relieves Itch from Skin Irritation, Insect Bites, Psoriasis, Skin Rashes, Eczema, & Poison Ivy, 2 oz

Lotrimin Ultra Jock Itch Cream - Powerful Butenafine Hydrochloride Treatment for Jock Itch, 0.42 Ounce (12 Grams) (Packaging May Vary)

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