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Best eye drops for severe dry eyes - Holiday Sale 2025

Last Updated - December 14, 2025

1
Best Choice

✖
Our rankings are cleverly generated from the algorithmic analysis of thousands of customer reviews about products, brands, merchant’s customer service level, popularity, trends and more. The rankings reflect our opinion and should be a good starting point for shopping.

Optase

Optase MGD Advanced Dry Eye Drops - .33 fl oz, 300 Doses

Optase

$24.80

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Main highlights
- OPTASE MGD Advanced Dry Eye Drops - .33 fl oz, 300 Doses
$24.80
2

✖
Our rankings are cleverly generated from the algorithmic analysis of thousands of customer reviews about products, brands, merchant’s customer service level, popularity, trends and more. The rankings reflect our opinion and should be a good starting point for shopping.

Optase

OPTASE Dry Eye Intense Drops - Preservative Free Eye Drops - Multidose Bottle - Step 3 Hydrate - .33 fl oz, 300 Doses

Optase

$23.98

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Main highlights
- Optase Dry Eye Intense Drops - .33 fl oz, 300 Doses
$23.98
3
Best Value
25% Off

✖
Our rankings are cleverly generated from the algorithmic analysis of thousands of customer reviews about products, brands, merchant’s customer service level, popularity, trends and more. The rankings reflect our opinion and should be a good starting point for shopping.

Systane
25% Off

Systane Ultra Lubricant Eye Drops, Artificial Tears for Dry Eye, Twin Pack, 10-mL Each

Systane

$18.99

$25.49
(25% Off)

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Main highlights
- Reduces both the signs and symptoms of dry eye
- Quickly soothe irritated eyes wherever you are
- Fast Long-Lasting Dry Eye Symptom Relief.Store at room temperature
- Extended Protection
- #1 Dr Recommended Brand of Artificial Tears*, packaging may vary
$18.99
$25.49 (25% Off)
4

✖
Our rankings are cleverly generated from the algorithmic analysis of thousands of customer reviews about products, brands, merchant’s customer service level, popularity, trends and more. The rankings reflect our opinion and should be a good starting point for shopping.

BLINK

BLINK Triple Care Eye Drops for Dry Eyes, Lubricant Eye Drops, Soothing for Moderate to Severe Dry Eyes, with Hyaluronate, Reduces Discomfort, Long-Lasting Hydration, 0.34 Fl Oz

BLINK

$13.29

More Details
Main highlights
- Trusted Brand: Blink has a range of products to meet your eye and contact lens care needs, from drops for dry eyes to lock in moisture, to preservative-free formulas; and contact lens drops to keep your contacts clean and hydrated. Blink products provide comfort and hydration, to help your eyes feel moisturized & protected
- Relief with every Blink: Experience extended dry eye symptom relief with Blink Triple Care Lubricating Eye Drops. This 3-in-1 formula instantly soothes, gives extra long-lasting hydration, and seals in moisture.
- Reduce Everyday Discomfort: These dops for dry eyes deliver extended relief for moderate to severe dry eye symptoms
- Long-Lasting Hydration: Blink Triple Care Lubricating Eye Drops are formulated with hyaluronate - also found in your eyes - to boost hydration. Hydrate like your tears for extra long-lasting comfort
- Dry Eye Lubricant: Discover what makes Blink Triple Care Lubricating Eye Drops different from other eye drops. Our drops for dry eyes have a dual-action moisture seal to lock in moisture for instant, long-lasting relief. The secret to our drops is a water-based formula enhanced with natural oil, which helps keep tears from evaporating too quickly
$13.29
5
22% Off

✖
Our rankings are cleverly generated from the algorithmic analysis of thousands of customer reviews about products, brands, merchant’s customer service level, popularity, trends and more. The rankings reflect our opinion and should be a good starting point for shopping.

Refresh
22% Off

Refresh Optive MEGA-3 Lubricant Eye Drops Preservative-Free Artificial Tears, 0.01 fl oz (0.4 mL), 30 Single-Use Containers

Refresh

$17.00

$21.99
(22% Off)

More Details
Main highlights
- TRUSTED: From the #1 doctor-recommended preservative-free brand with over 35 years of experience (Data on file, AbbVie, Inc. REF113774)
- TRIPLE-ACTION FORMULA: Lubricates, hydrates, and protects tears from evaporating
- PRESERVATIVE-FREE: Enhanced with antioxidants and plant-based Flaxseed Oil (inactive ingredients) which contains omega-3s
- ON-THE-GO VIALS: 30 sterile single-use vials per carton that are easy and safe to use as often as needed
- LASTING RELIEF: Soothes and prevents further irritation
- FSA & HSA ELIGIBLE: Your pre-tax dollars may cover this product as an out-of-pocket expense depending on your plan
- FAST-ACTING: Rapid relief to comfort dry, irritated eyes
- ADVANCED HYDRATION: Innovated with patented HydroCell technology that enables rehydration
$17.00
$21.99 (22% Off)

Best eye drops for severe dry eyes - Holiday Sale 2025

Optase MGD Advanced Dry Eye Drops - .33 fl oz, 300 Doses

OPTASE Dry Eye Intense Drops - Preservative Free Eye Drops - Multidose Bottle - Step 3 Hydrate - .33 fl oz, 300 Doses

Systane Ultra Lubricant Eye Drops, Artificial Tears for Dry Eye, Twin Pack, 10-mL Each

BLINK Triple Care Eye Drops for Dry Eyes, Lubricant Eye Drops, Soothing for Moderate to Severe Dry Eyes, with Hyaluronate, Reduces Discomfort, Long-Lasting Hydration, 0.34 Fl Oz

Refresh Optive MEGA-3 Lubricant Eye Drops Preservative-Free Artificial Tears, 0.01 fl oz (0.4 mL), 30 Single-Use Containers

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