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Best enzymatic cleaners for pet urines - Holiday Sale 2025

Last Updated - December 14, 2025

1
Best Choice

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Our rankings are cleverly generated from the algorithmic analysis of thousands of customer reviews about products, brands, merchant’s customer service level, popularity, trends and more. The rankings reflect our opinion and should be a good starting point for shopping.

Rocco & Roxie Supply Co.

Rocco & Roxie Supply Co. Stain & Strong Odor Eliminator, Enzyme Cleaner, Pet Odor Eliminator for Home - Carpet Stain Remover for Cats & Dog Pee - Urine Destroyer - Carpet Cleaner Spray, 1-Gallon

Picked by 673 people in the last week

Rocco & Roxie Supply Co.

$59.97

More Details
Main highlights
- Pet Enzyme Carpet Cleaner for Stains, Odors, Residue: If it's gross, it's gone; the stain and the stink; from stinky yellow pet urine, feces to vomit or other organic spills, Rocco & Roxie professional strength stain & odor eliminator tackles it all
- Certified Gentle & Safe Pet Carpet Cleaner Solution: Chlorine free, color safe, no hazardous propellants or residue; safe to use around pets and children; certified safe for all carpets with a Seal of Approval by the Carpet and Rug Institute (CRI)
- Cat & Dog Urine Enzyme Cleaner for Every Surface, Every Time: For use on carpets, floors, furniture, clothing, litter boxes, kennels, carriers, all pet living and sleeping areas—anywhere stains happen enzyme cleaner for dog urine
- Cat & Dog Urine Enzyme Cleaner for Every Surface, Every Time: For use on carpets, floors, furniture, clothing, litter boxes, kennels, carriers, all pet living and sleeping areas—anywhere stains happen enzyme cleaner for dog urine
- Buy With Confidence: You want the best for your best friend; we do, too; if you are not satisfied with the performance of this Rocco & Roxie stain & odor eliminator, contact us; we are determined to make it right
$59.97
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Our rankings are cleverly generated from the algorithmic analysis of thousands of customer reviews about products, brands, merchant’s customer service level, popularity, trends and more. The rankings reflect our opinion and should be a good starting point for shopping.

Biokleen

Biokleen Bac-Out Enzyme Stain & Odor Remover - 128 Ounces - Destroys Stains & Odors Safely, for Pet Stains, Laundry, Diapers, Wine, Carpets, & More, Eco-Friendly, Non-Toxic

Biokleen

$34.98

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Main highlights
- STAIN AND ODOR REMOVER: Bac-Out safely works wonders on pet accidents, wine spills on carpets and couches, cloth diapers and pails, laundry, disposals, garbage cans and much more.
- PREFERRED BY PROFFESSIONALS: Bac-Out is the preferred choice of commercial carpet cleaners nationwide.
- PLANT BASED CLEANER: Bac-Out uses a plant-based, eco-friendly solution with no artificial fragrances or dyes. Our products never contain phosphates, chlorine, ammonia, or brighteners.
- MADE IN THE USA: We use biodegradable ingredients, never test on animals, and are manufactured in the USA with US and imported parts
- BIO ACTIVE FORMULA: A unique blend of live enzyme cultures breakdown and absorb organic material. It's a more natural way to remove buildup and stinky odors.
$34.98
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Our rankings are cleverly generated from the algorithmic analysis of thousands of customer reviews about products, brands, merchant’s customer service level, popularity, trends and more. The rankings reflect our opinion and should be a good starting point for shopping.

Bioda

Bioda Multi-Purpose Probiotic Enzyme Cleaner and Deodorizer | Professional Strength | Trash Can Deodorizer, Pet Stains and Odors, Drains, Floors, Bathrooms, Toilets | Made in USA | 1 Gallon

Bioda

$25.99

More Details
Main highlights
- THE POWER OF ONE: This versatile product is the only probiotic cleaner you need, providing powerful cleaning performance in a wide variety of applications. Multipurpose use: Maintain clean drain lines and septic tanks to prevent clogs and potential buildup. Clean and deodorize trash bins, stains and odors on floors, carpets, bathroom surfaces, kitchen surfaces, and more.
- NATURALLY, SUPERIOR RESULTS: A special blend of enzyme-producing probiotics break down complex proteins, fats, oils, greases, and other organic waste. The enzymes digest the soils until they have been eliminated, providing a long-lasting, continuous clean without leaving a residue or harmful by-products behind.
- MADE IN THE USA - 1 Gallon Bottle
- ELIMINATE ODOR: Provide total odor control by eliminating the actual source of even the most pungent organic malodors naturally, including rotting food, urine, feces, vomit, and trash. Plus, the fresh lemon and sage fragrance leaves behind a light, pleasant scent that rejuvenates the air of any environment.
- ACTIVE UP TO 21 DAYS: Our specialized probiotics continue to clean soils in cracks, grout and tough to reach places. Simply spray & let the probiotics do the dirty work!
$25.99
4
Best Value

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Our rankings are cleverly generated from the algorithmic analysis of thousands of customer reviews about products, brands, merchant’s customer service level, popularity, trends and more. The rankings reflect our opinion and should be a good starting point for shopping.

KINZUA ENVIRONMENTAL

KINZUA ENVIRONMENTAL Urine B-Gone, Professional Enzyme Odor Eliminator & Pet Stain Remover, Human, Cat & Dog Urine Cleaner, Effective on Laundry, Carpets & More, Lavender Scent, 1 Gallon

KINZUA ENVIRONMENTAL

$34.45

More Details
Main highlights
- Versatile Cleaning Solution: Beyond pet stains, Urine B-Gone is ideal for a variety of applications; Use it in your laundry to pre-spray soiled areas or even in drains, urinals, and toilets; This all-in-one cleaner & odor remover makes tackling tough stains and odors simple and efficient
- Safe for Your Home: Our natural enzyme formula is safe to use around pets and children when used as directed; It’s designed to be gentle yet highly effective, providing peace of mind while maintaining a clean and odor-free environment; Enjoy the fresh scent of our urine cleaner
- Powerful & Effective Cleaner: Each gallon of Urine B-Gone is loaded with 200 billion microbe colonies, working tirelessly to liquefy, digest, and completely eliminate urine and poop; This high-strength formula ensures your home stays fresh and free from unpleasant odors while leaving behind a soothing lavender fragrance
- Deep Penetration, Lasting Results: Urine B-Gone doesn’t just mask odors; it attacks them at the source; This powerful enzyme cleaner penetrates deep into any carpet and upholstery, removing stains and neutralizing smells even from padding and the floor beneath; Its versatile formula makes it suitable for all cleaning tasks, ensuring every surface is left fresh and spotless
- About Us: At Kinzua Environmental, we specialize in premium cleaning solutions that are safe and professional strength for both commercial and household applications
$34.45
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Our rankings are cleverly generated from the algorithmic analysis of thousands of customer reviews about products, brands, merchant’s customer service level, popularity, trends and more. The rankings reflect our opinion and should be a good starting point for shopping.

ACTIVE

Pet Odor and Stain Eliminator - 32 oz ACTIVE Enzyme Cleaner for Dog & Cat Urine, Stain Remover Spray for Carpet, Upholstery, Hardwood, Spot Cleaning, Deodorizer for Dogs Cats Pets - Natural Citrus Oil

ACTIVE

$19.95

More Details
Main highlights
- Proudly Made in USA: ACTIVE Pet Odor Neutralizer Spray is made entirely in the United States with just the best components and ingredients. Our Formula is gentle yet Effective, and Safe to use around Pets and Kids
- Professional Stain Removal: ACTIVE Enzyme Cleaners will easily get rid of mess and set-in stains in Carpets, Fabric, Floor. Our powerful Stain Eliminating Solution creates a Deep Cleaning Lather with every Spray for full Stain Treatment
- Product Usage Instructions: Spray directly onto the pet stain and surrounding area to ensure full and even coverage. Allow the solution to soak up to one hour so it can get deep into the carpet, rug, or upholstery fibers to break down stains and odor-causing residues. After soaking, blot the area with a clean cloth to lift grime & debris. For tough stains, apply more cleaner, lightly agitate the area with a soft brush or cloth, and reapply as needed. Finish by wiping the area dry or extract remaining moisture with carpet cleaner for best results
- Designed for Home Surfaces: Universal Indoor Pet Clean-up Spray for couch stains, Wood Floors, Rug, Furniture, Mattress, Dog bed, Kennel- wherever your pet goes! Get any hard to clean accident in the house with ACTIVE deodorizers and animal stain removers
- Completely Eliminate Odors & Stains: Our ready-to-use Advanced Pet Odor Eliminator Sprays target the source of animal messes, Lifting Stains and Removing Smells, leaving behind only a Pleasant Citrus Oil Scent! Compare to other products that only mask the problem instead of actually deodorizing
- Bio Enzymatic Odor Destroyer: ACTIVE Pet Stain and Odor Remover Formula is specially made with Enzymes and Natural Probiotics that Remove Smell from Puppy Accidents, Cat Urine, and all odour from Pee, Poop, Vomit, Litter and more
$19.95

Best enzymatic cleaners for pet urines - Holiday Sale 2025

Rocco & Roxie Supply Co. Stain & Strong Odor Eliminator, Enzyme Cleaner, Pet Odor Eliminator for Home - Carpet Stain Remover for Cats & Dog Pee - Urine Destroyer - Carpet Cleaner Spray, 1-Gallon

Biokleen Bac-Out Enzyme Stain & Odor Remover - 128 Ounces - Destroys Stains & Odors Safely, for Pet Stains, Laundry, Diapers, Wine, Carpets, & More, Eco-Friendly, Non-Toxic

Bioda Multi-Purpose Probiotic Enzyme Cleaner and Deodorizer | Professional Strength | Trash Can Deodorizer, Pet Stains and Odors, Drains, Floors, Bathrooms, Toilets | Made in USA | 1 Gallon

KINZUA ENVIRONMENTAL Urine B-Gone, Professional Enzyme Odor Eliminator & Pet Stain Remover, Human, Cat & Dog Urine Cleaner, Effective on Laundry, Carpets & More, Lavender Scent, 1 Gallon

Pet Odor and Stain Eliminator - 32 oz ACTIVE Enzyme Cleaner for Dog & Cat Urine, Stain Remover Spray for Carpet, Upholstery, Hardwood, Spot Cleaning, Deodorizer for Dogs Cats Pets - Natural Citrus Oil

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