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Best enzymatic cleaners for cat urines - Holiday Sale 2025

Last Updated - December 14, 2025

1
Best Choice
10% Off

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Our rankings are cleverly generated from the algorithmic analysis of thousands of customer reviews about products, brands, merchant’s customer service level, popularity, trends and more. The rankings reflect our opinion and should be a good starting point for shopping.

ANGRY ORANGE
10% Off

ANGRY ORANGE Pet Odor Eliminator for Dog and Cat Urine, Carpet Stains, and Strong Smells – Citrus Cleaner with Natural Orange Oil – 24 oz

Picked by 1128 people in the last week

ANGRY ORANGE

$17.96

$19.97
(10% Off)

More Details
Main highlights
- SCENT POWERED BY NATURAL ORANGE OIL – Has the power of real orange oil, leaving a pleasant citrus scent behind without harsh smells.
- SAFE FOR HOMES WITH PETS WHEN USED AS DIRECTED – No added parabens, sulfates, or phthalates. No chemical stink. Powerful cleaning without the harsh stink.
- MADE IN THE USA – Proudly formulated and manufactured in the USA for pet owners who care about quality and safety.
- DESTROYS TOUGH PET ODORS – Tackles strong smells from dog and cat urine, feces, vomit, and more. Works fast to eliminate lingering odors at the source.
- CLEANS STAINS ON FLOORS & MORE – Designed for use on hard and sealed surfaces where pet messes happen most. Works fast to eliminate lingering odors at the source.
$17.96
$19.97 (10% Off)
2

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Our rankings are cleverly generated from the algorithmic analysis of thousands of customer reviews about products, brands, merchant’s customer service level, popularity, trends and more. The rankings reflect our opinion and should be a good starting point for shopping.

Rocco & Roxie Supply Co.

Rocco & Roxie Supply Co. Stain & Strong Odor Eliminator, Enzyme Cleaner, Pet Odor Eliminator for Home - Carpet Stain Remover for Cats & Dog Pee - Urine Destroyer - Carpet Cleaner Spray, 1-Gallon

Rocco & Roxie Supply Co.

$59.97

More Details
Main highlights
- Pet Enzyme Carpet Cleaner for Stains, Odors, Residue: If it's gross, it's gone; the stain and the stink; from stinky yellow pet urine, feces to vomit or other organic spills, Rocco & Roxie professional strength stain & odor eliminator tackles it all
- Certified Gentle & Safe Pet Carpet Cleaner Solution: Chlorine free, color safe, no hazardous propellants or residue; safe to use around pets and children; certified safe for all carpets with a Seal of Approval by the Carpet and Rug Institute (CRI)
- Cat & Dog Urine Enzyme Cleaner for Every Surface, Every Time: For use on carpets, floors, furniture, clothing, litter boxes, kennels, carriers, all pet living and sleeping areas—anywhere stains happen enzyme cleaner for dog urine
- Cat & Dog Urine Enzyme Cleaner for Every Surface, Every Time: For use on carpets, floors, furniture, clothing, litter boxes, kennels, carriers, all pet living and sleeping areas—anywhere stains happen enzyme cleaner for dog urine
- Buy With Confidence: You want the best for your best friend; we do, too; if you are not satisfied with the performance of this Rocco & Roxie stain & odor eliminator, contact us; we are determined to make it right
$59.97
3

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Our rankings are cleverly generated from the algorithmic analysis of thousands of customer reviews about products, brands, merchant’s customer service level, popularity, trends and more. The rankings reflect our opinion and should be a good starting point for shopping.

Biokleen

Biokleen Bac-Out Enzyme Stain & Odor Remover - 128 Ounces - Destroys Stains & Odors Safely, for Pet Stains, Laundry, Diapers, Wine, Carpets, & More, Eco-Friendly, Non-Toxic

Biokleen

$34.98

More Details
Main highlights
- STAIN AND ODOR REMOVER: Bac-Out safely works wonders on pet accidents, wine spills on carpets and couches, cloth diapers and pails, laundry, disposals, garbage cans and much more.
- PREFERRED BY PROFFESSIONALS: Bac-Out is the preferred choice of commercial carpet cleaners nationwide.
- PLANT BASED CLEANER: Bac-Out uses a plant-based, eco-friendly solution with no artificial fragrances or dyes. Our products never contain phosphates, chlorine, ammonia, or brighteners.
- MADE IN THE USA: We use biodegradable ingredients, never test on animals, and are manufactured in the USA with US and imported parts
- BIO ACTIVE FORMULA: A unique blend of live enzyme cultures breakdown and absorb organic material. It's a more natural way to remove buildup and stinky odors.
$34.98
4
Best Value
15% Off

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Our rankings are cleverly generated from the algorithmic analysis of thousands of customer reviews about products, brands, merchant’s customer service level, popularity, trends and more. The rankings reflect our opinion and should be a good starting point for shopping.

Nature's Miracle
15% Off

Nature's Miracle Urine Destroyer Plus for Cats, Enzymatic Formula for Severe Cat Urine Stains, 1 Gal

Nature's Miracle

$31.67

$37.49
(15% Off)

More Details
Main highlights
- TRUSTED BRAND: From the maker of Nature’s Miracle products, the pet stain and odor removing brand you trust… because it works!
- SAFE FOR PETS AND HOME: When used and stored as directed, this formula can be used around your pets and in your home.
- GREAT FOR REFILLS: The 128-ounce bottle is easy to pour and great for refilling smaller bottles.
- FOR CAT URINE MESSES: Begins to break down and remove stains immediately on contact.
- ENZYMATIC FORMULA: Continues working as long as any bio-based mess is still present.
$31.67
$37.49 (15% Off)
5

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Our rankings are cleverly generated from the algorithmic analysis of thousands of customer reviews about products, brands, merchant’s customer service level, popularity, trends and more. The rankings reflect our opinion and should be a good starting point for shopping.

Bioda

Bioda Multi-Purpose Probiotic Enzyme Cleaner and Deodorizer | Professional Strength | Trash Can Deodorizer, Pet Stains and Odors, Drains, Floors, Bathrooms, Toilets | Made in USA | 1 Gallon

Bioda

$25.99

More Details
Main highlights
- THE POWER OF ONE: This versatile product is the only probiotic cleaner you need, providing powerful cleaning performance in a wide variety of applications. Multipurpose use: Maintain clean drain lines and septic tanks to prevent clogs and potential buildup. Clean and deodorize trash bins, stains and odors on floors, carpets, bathroom surfaces, kitchen surfaces, and more.
- NATURALLY, SUPERIOR RESULTS: A special blend of enzyme-producing probiotics break down complex proteins, fats, oils, greases, and other organic waste. The enzymes digest the soils until they have been eliminated, providing a long-lasting, continuous clean without leaving a residue or harmful by-products behind.
- MADE IN THE USA - 1 Gallon Bottle
- ELIMINATE ODOR: Provide total odor control by eliminating the actual source of even the most pungent organic malodors naturally, including rotting food, urine, feces, vomit, and trash. Plus, the fresh lemon and sage fragrance leaves behind a light, pleasant scent that rejuvenates the air of any environment.
- ACTIVE UP TO 21 DAYS: Our specialized probiotics continue to clean soils in cracks, grout and tough to reach places. Simply spray & let the probiotics do the dirty work!
$25.99

Best enzymatic cleaners for cat urines - Holiday Sale 2025

ANGRY ORANGE Pet Odor Eliminator for Dog and Cat Urine, Carpet Stains, and Strong Smells – Citrus Cleaner with Natural Orange Oil – 24 oz

Rocco & Roxie Supply Co. Stain & Strong Odor Eliminator, Enzyme Cleaner, Pet Odor Eliminator for Home - Carpet Stain Remover for Cats & Dog Pee - Urine Destroyer - Carpet Cleaner Spray, 1-Gallon

Biokleen Bac-Out Enzyme Stain & Odor Remover - 128 Ounces - Destroys Stains & Odors Safely, for Pet Stains, Laundry, Diapers, Wine, Carpets, & More, Eco-Friendly, Non-Toxic

Nature's Miracle Urine Destroyer Plus for Cats, Enzymatic Formula for Severe Cat Urine Stains, 1 Gal

Bioda Multi-Purpose Probiotic Enzyme Cleaner and Deodorizer | Professional Strength | Trash Can Deodorizer, Pet Stains and Odors, Drains, Floors, Bathrooms, Toilets | Made in USA | 1 Gallon

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