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Best digestive supplements - Holiday Sale 2025

Last Updated - December 14, 2025

1
Best Choice
13% Off

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Our rankings are cleverly generated from the algorithmic analysis of thousands of customer reviews about products, brands, merchant’s customer service level, popularity, trends and more. The rankings reflect our opinion and should be a good starting point for shopping.

Physician's CHOICE
13% Off

Physician's CHOICE Probiotics 60 Billion CFU - 10 Strains + Organic Prebiotics - Immune, Digestive & Gut Health - Supports Occasional Constipation, Diarrhea, Gas & Bloating - for Women & Men - 60ct

Picked by 353 people in the last week

Physician's CHOICE

$36.97

$42.52
(13% Off)

More Details
Main highlights
- Survives the Gut: From start to finish - this probiotic is designed to survive the gut & maximize the colonization of our strains. We use a shelf-stable bottle, acid-resistant capsules, and 60 Billion Colony forming units (CFU) to achieve this!
- Support Your Gut: Our probiotic contains 10 diverse high-quality probiotic strains and organic prebiotics - synergistically working together to support your gut health. Expertly crafted to support occasional constipation, diarrhea, gas & bloating!
- Safety Assured Standard of Quality: Our 60B probiotic is 3rd-party tested for purity and potency. Each bottle is manufactured with love & care in the USA with strict quality control - using imported and domestic ingredients.
- Max Strength General Probiotic 2 Month Supply (60ct) : Our probiotic is designed to support digestive health & gut health. A great choice for those looking to support a diverse healthy microbiome w/ 60B CFU - Probiotics for Women & Men alike. Same great product you love, with a new look. Packaging May Vary!
- Backed By Science - Our probiotics are crafted based on scientific research. We have partnered with a network of expert physicians to help review our products & research. We strive to educate & help you with informed decisions regarding your health.
$36.97
$42.52 (13% Off)
2
10% Off

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Our rankings are cleverly generated from the algorithmic analysis of thousands of customer reviews about products, brands, merchant’s customer service level, popularity, trends and more. The rankings reflect our opinion and should be a good starting point for shopping.

Metamucil
10% Off

Metamucil, Psyllium Husk Capsules, 300 Capsules, 3-in-1 Fiber Supplement, Daily Psyllium Husk Fiber Capsules Help Support Digestive Health by Promoting Regularity*, Help Supplement Daily Fiber Intake

Metamucil

$32.32

$35.99
(10% Off)

More Details
Main highlights
- PSYLLIUM HUSK FIBER CAPSULES help support: digestive health*, heart health by lowering cholesterol, and healthy blood sugar levels*.
- PROMOTE DIGESTIVE HEALTH & REGULARITY*. Metamucil psyllium fiber capsules help trap and remove the waste*.
- MULTIPLE HEALTH BENEFITS* in daily fiber capsules. Metamucil is the only leading fiber brand made with psyllium husk fiber
- DAILY FIBER CAPSULES. Metamucil fiber capsules are designed for daily use. No spoon or mixing required!
- 1 IN 10 AMERICANS GET ENOUGH FIBER from diet alone. Help close your fiber gap by taking Metamucil fiber capsules daily.
- #1 DOCTOR RECOMMENDED fiber brand. Trusted for over 90 years.
$32.32
$35.99 (10% Off)
3
Best Value
15% Off

✖
Our rankings are cleverly generated from the algorithmic analysis of thousands of customer reviews about products, brands, merchant’s customer service level, popularity, trends and more. The rankings reflect our opinion and should be a good starting point for shopping.

Physician's CHOICE
15% Off

Physician's CHOICE Digestive Enzymes for Bloating & Digestion - 16 Enzymes with Organic Prebiotics & Probiotics for Gut & Digestive Health - Meal Time Discomfort Relief - Dual Action Support - 60 CT

Physician's CHOICE

$19.97

$23.52
(15% Off)

More Details
Main highlights
- Science Backed - Our Digestive Enzyme Probiotics are crafted based on scientific research. We have partnered with expert physicians to help review our products & research. We strive to educate & help you with informed decisions regarding your health.
- Safety Assured Standard of Quality: Our Digestive Enzymes are 3rd-party tested for purity and potency. Each bottle is manufactured w/ love & care in the USA with strict quality control - using imported & domestic ingredients. No Refrigeration Needed
- Probiotics that Survive the Gut: Formulated with 3 soil-based probiotic strains - specifically selected due to their ability to survive the harsh gut environment. Along with Organic Prebiotics that fuel the growth of healthy bacteria in the gut.
- Dual Action Relief: Our powerful digestive enzymes aid with breaking down food while the prebiotics & probiotics promote digestive function in the gut. They work synergistically to provide relief from mealtime discomfort. One Month Supply
- Beat the Bloat & Say Goodbye to Meal Time Discomfort: 16 beneficial enzymes that digest proteins, carbs, fruits, veggies, beans, dairy, & fats to cover all diets. With SBO Probiotics & Prebiotics to aid digestion further - Your New Meal Time Hack! Same great product you love, with a new look. Packaging May Vary!
$19.97
$23.52 (15% Off)
4

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Our rankings are cleverly generated from the algorithmic analysis of thousands of customer reviews about products, brands, merchant’s customer service level, popularity, trends and more. The rankings reflect our opinion and should be a good starting point for shopping.

Zenwise Health

Zenwise Health Digestive Enzymes for Gut Health & Bloating Relief - Multi Enzymes Digestion Supplement with Probiotics, Bromelain & Papaya for Digestive Health Support - Men & Women - 60 Count

Zenwise Health

$19.97

More Details
Main highlights
- Proven Probiotics – Guaranteed to arrive alive and work within hours in the small intestine where 90% of nutrient absorption occurs, helping support overall digestive health.
- Plant-Based Formula – Pure vegetarian enzymes, including bromelain and papain, combined with prebiotic fiber nourish your microbiome while supporting healthy digestion and immune function. Take 1 capsule before your meal to experience digestive delight.
- Gas & Bloating Relief – Targeted enzymes, including bromelain and papaya, work with beneficial microflora to ease uncomfortable bloating, reduce gas, and soothe digestive discomfort naturally.
- Fast-Acting Enzymes – Featuring powerful enzymes like bromelain (from pineapple) and papain (from papaya), this blend starts working immediately to break down food up to 39% more completely, easing indigestion for rapid, noticeable relief.
- 3-in-1 Formula – A potent blend of lab-proven enzymes, including bromelain and papaya, clinically proven probiotics, and prebiotics work synergistically to break down proteins, fats, and carbs while restoring digestive flora balance for optimal nutrient absorption and digestion. This formula helps maintain digestive wellness and promotes regularity.
$19.97
5

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Our rankings are cleverly generated from the algorithmic analysis of thousands of customer reviews about products, brands, merchant’s customer service level, popularity, trends and more. The rankings reflect our opinion and should be a good starting point for shopping.

NOW Foods

NOW Foods Supplements, Super Enzymes, Formulated with Bromelain, Ox Bile, Pancreatin and Papain,180 Capsules

NOW Foods

$24.99

More Details
Main highlights
- SUPPORTS HEALTHY DIGESTION*: NOW Super Enzymes is a comprehensive blend of enzymes that supports healthy digestion.* Take one capsule with a meal
- Packaged in the USA by a family owned and operated company since 1968
- GMP Quality Assured: NPA A-rated GMP certification means that every aspect of the NOW manufacturing process has been examined, including our laboratory/testing methods (for stability, potency, and product formulation)
- CERTIFICATIONS/CLASSIFICATIONS: Soy Free, Made without Gluten, Keto Friendly
- BREAKS DOWN FATS, CARBS, AND PROTEINS*/OPTIMIZES NUTRIENT AVAILABILITY*: Formulated with bromelain, ox bile, pancreatin and papain, Super Enzymes helps to optimize the breakdown of fats, carbohydrates and protein*
$24.99

Best digestive supplements - Holiday Sale 2025

Physician's CHOICE Probiotics 60 Billion CFU - 10 Strains + Organic Prebiotics - Immune, Digestive & Gut Health - Supports Occasional Constipation, Diarrhea, Gas & Bloating - for Women & Men - 60ct

Metamucil, Psyllium Husk Capsules, 300 Capsules, 3-in-1 Fiber Supplement, Daily Psyllium Husk Fiber Capsules Help Support Digestive Health by Promoting Regularity*, Help Supplement Daily Fiber Intake

Physician's CHOICE Digestive Enzymes for Bloating & Digestion - 16 Enzymes with Organic Prebiotics & Probiotics for Gut & Digestive Health - Meal Time Discomfort Relief - Dual Action Support - 60 CT

Zenwise Health Digestive Enzymes for Gut Health & Bloating Relief - Multi Enzymes Digestion Supplement with Probiotics, Bromelain & Papaya for Digestive Health Support - Men & Women - 60 Count

NOW Foods Supplements, Super Enzymes, Formulated with Bromelain, Ox Bile, Pancreatin and Papain,180 Capsules

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Nutricost Digestive Enzymes 620mg, 120 Capsules - Complete Digestive Enzyme Supplement

Zenwise Health Digestive Enzymes for Gut Health & Bloating Relief - Multi Enzymes Digestion Supplement with Probiotics, Bromelain & Papaya for Digestive Health Support - Men & Women - 100 Count

Physician's CHOICE Probiotics for Women - PH Balance, Digestive, UT, & Feminine Health - 50 Billion CFU - 6 Unique Strains for Her - Organic Prebiotics, Cranberry Extract+ - Women Probiotic - 30 CT

OLLY Probiotic + Prebiotic Gummy, Digestive Support and Gut Health, 500 Million CFUs, Fiber, Adult Chewable Supplement for Men and Women, Peach, 30 Day Supply - 30 Count

Nature's Bounty Lactobacillus Acidophilus Probiotic Supplement - Daily Probiotic for Women/Men Digestive Health, 100 Million Organisms, Vegetarian, 1 Serving per Day, 120 Tablets

Horbäach Essential Digestive Enzymes | 250 Capsules | Powerful Enzyme Blend for Men & Women | Non-GMO & Gluten Free Supplement

Benefiber On The Go Prebiotic Fiber Supplement Powder for Digestive Health, Daily Fiber, Unflavored - 28 Sticks (3.92 Ounces)

Digestive Enzymes - 800mg Blend of All 10 Most Essential Digestive and Pancreatic Enzymes (Amylase, Lipase, Bromelain, Lactase, Papain, Protease, Cellulase, Maltase, Invertase) by Double Wood

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