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Best diaper creams - April 2026

Last Updated - April 1, 2026

1
Best Choice
27% Off

✖
Our rankings are cleverly generated from the algorithmic analysis of thousands of customer reviews about products, brands, merchant’s customer service level, popularity, trends and more. The rankings reflect our opinion and should be a good starting point for shopping.

Desitin
27% Off

Desitin Maximum Strength Baby Diaper Rash Cream, 40% Zinc Oxide for Treatment, Relief & Prevention, Hypoallergenic, Phthalate- & Paraben-Free Paste, Protects Skin For Up To 12 Hours, 16 oz

Desitin

$19.48

$26.66
(27% Off)

More Details
Main highlights
- The maximum strength paste provides effective diaper rash relief by immediately forming a protective barrier on baby's skin to seal out wetness and soothe chafed skin
- The baby diaper rash paste's hypoallergenic formula is paraben-, phthalate-, and dye-free. It is also Dermatologist- and Pediatrician-tested and is gentle enough for daily use
- Rich, thick diaper rash cream is formulated with 40% maximum-level zinc oxide and is clinically shown to protect baby's delicate skin for up to 12 hours
- Maximum strength diaper rash paste provides 5-in-1 action to treat, heal, protect, soothe & help prevent diaper rash, for healing you can see & relief your baby can feel. Apply paste as often as needed or when exposure to wet diapers may be prolonged
- 16-ounce jar of Desitin Maximum Strength Diaper Rash Paste with 40% zinc oxide works on contact to treat and help prevent baby diaper rash discomfort
$19.48
$26.66 (27% Off)
2
Best Value
31% Off

✖
Our rankings are cleverly generated from the algorithmic analysis of thousands of customer reviews about products, brands, merchant’s customer service level, popularity, trends and more. The rankings reflect our opinion and should be a good starting point for shopping.

Desitin
31% Off

Desitin Maximum Strength Baby Diaper Rash Cream, 40% Zinc Oxide for Treatment, Relief & Prevention, Hypoallergenic, Phthalate- & Paraben-Free Paste, Protects Skin For Up To 12 Hours, 16 oz

Desitin

$18.51

$26.66
(31% Off)

More Details
Main highlights
- The maximum strength paste provides effective diaper rash relief by immediately forming a protective barrier on baby's skin to seal out wetness and soothe chafed skin
- The baby diaper rash paste's hypoallergenic formula is paraben-, phthalate-, and dye-free. It is also Dermatologist- and Pediatrician-tested and is gentle enough for daily use
- Rich, thick diaper rash cream is formulated with 40% maximum-level zinc oxide and is clinically shown to protect baby's delicate skin for up to 12 hours
- Maximum strength diaper rash paste provides 5-in-1 action to treat, heal, protect, soothe & help prevent diaper rash, for healing you can see & relief your baby can feel. Apply paste as often as needed or when exposure to wet diapers may be prolonged
- 16-ounce jar of Desitin Maximum Strength Diaper Rash Paste with 40% zinc oxide works on contact to treat and help prevent baby diaper rash discomfort
$18.51
$26.66 (31% Off)
3

✖
Our rankings are cleverly generated from the algorithmic analysis of thousands of customer reviews about products, brands, merchant’s customer service level, popularity, trends and more. The rankings reflect our opinion and should be a good starting point for shopping.

A+D

A+D Original Diaper Rash Ointment Prevents & Treats Diaper Rash, Moisturizing Skin Protectant with Vitamins A & D, Healing Skin Ointment for Dry and Cracked Skin 16 oz

A+D

$14.47

More Details
Main highlights
- WORKS ON CONTACT: Our soothing diaper cream works on contact to help treat & calm irritated skin. Use at the first sign of diaper rash as soon as redness and irritation develops under the diaper
- WASH, DRY, APPLY: This gentle zinc oxide diaper rash cream is smooth, non-greasy and spreads evenly. Wash the area with soap and water, gently pat with dry cloth, apply cream to protect the area
- TRUSTED FOR 80 YEARS: For over 80 years, A+D vitamin enriched formula has been trusted & endorsed by moms, dads, pediatricians, and dermatologists to heal the most sensitive skin. A+D is here to provide your family with more happy skin days
- TREATS DIAPER RASH: Dimethicone and Zinc Oxide combine for a diaper rash treatment that protects tender bottoms, allowing baby’s skin to heal naturally
- PEDIATRICIAN RECOMMENDED DIAPER RASH CREAM: A+D Diaper Rash Cream is pediatrician recommended and contains zinc oxide, dimethicone & soothing aloe to moisturize and protect the skin. Free of parabens, dyes, and phthalates
$14.47
4

✖
Our rankings are cleverly generated from the algorithmic analysis of thousands of customer reviews about products, brands, merchant’s customer service level, popularity, trends and more. The rankings reflect our opinion and should be a good starting point for shopping.

A+D

A+D Original Diaper Rash Ointment Prevents & Treats Diaper Rash, Moisturizing Skin Protectant with Vitamins A & D, Healing Skin Ointment for Dry and Cracked Skin 16 oz

A+D

$13.75

$14.47
(5% Off)

More Details
Main highlights
- WORKS ON CONTACT: Our soothing diaper cream works on contact to help treat & calm irritated skin. Use at the first sign of diaper rash as soon as redness and irritation develops under the diaper
- WASH, DRY, APPLY: This gentle zinc oxide diaper rash cream is smooth, non-greasy and spreads evenly. Wash the area with soap and water, gently pat with dry cloth, apply cream to protect the area
- TRUSTED FOR 80 YEARS: For over 80 years, A+D vitamin enriched formula has been trusted & endorsed by moms, dads, pediatricians, and dermatologists to heal the most sensitive skin. A+D is here to provide your family with more happy skin days
- TREATS DIAPER RASH: Dimethicone and Zinc Oxide combine for a diaper rash treatment that protects tender bottoms, allowing baby’s skin to heal naturally
- PEDIATRICIAN RECOMMENDED DIAPER RASH CREAM: A+D Diaper Rash Cream is pediatrician recommended and contains zinc oxide, dimethicone & soothing aloe to moisturize and protect the skin. Free of parabens, dyes, and phthalates
$13.75
$14.47 (5% Off)
5
11% Off

✖
Our rankings are cleverly generated from the algorithmic analysis of thousands of customer reviews about products, brands, merchant’s customer service level, popularity, trends and more. The rankings reflect our opinion and should be a good starting point for shopping.

Desitin
11% Off

Desitin Daily Defense Baby Diaper Rash Cream with 13% Zinc Oxide, Barrier Cream to Treat, Relieve & Prevent Diaper Rash, Hypoallergenic, Dye-, Phthalate- & Paraben-Free, 16 oz

Desitin

$15.98

$17.95
(11% Off)

More Details
Main highlights
- This diaper cream is specially formulated for babies' tender skin and is paraben-, phthalate-, fragrance- and dye-free so it's gentle enough to use daily at every diaper change
- Made with 13% zinc oxide skin protectant, its fast-acting hypoallergenic formula helps seal out wetness to treat diaper rash from the first signs and is clinically shown to provide diaper rash relief
- Its rich, creamy formula goes on smoothly and wipes off easily, making Desitin Daily Defense Diaper Rash Cream your trusted partner for treating diaper rash from the first signs
- From the #1 choice for diaper rash relief by Pediatricians and parents, this skin barrier cream instantly forms a protective layer on your baby's skin for diaper rash relief and prevention
- 16-ounce tub of Desitin Daily Defense Baby Diaper Rash Healing Cream works from the first use to help soothe, treat and prevent diaper rash
$15.98
$17.95 (11% Off)

Best diaper creams - April 2026

Desitin Maximum Strength Baby Diaper Rash Cream, 40% Zinc Oxide for Treatment, Relief & Prevention, Hypoallergenic, Phthalate- & Paraben-Free Paste, Protects Skin For Up To 12 Hours, 16 oz

Desitin Maximum Strength Baby Diaper Rash Cream, 40% Zinc Oxide for Treatment, Relief & Prevention, Hypoallergenic, Phthalate- & Paraben-Free Paste, Protects Skin For Up To 12 Hours, 16 oz

A+D Original Diaper Rash Ointment Prevents & Treats Diaper Rash, Moisturizing Skin Protectant with Vitamins A & D, Healing Skin Ointment for Dry and Cracked Skin 16 oz

A+D Original Diaper Rash Ointment Prevents & Treats Diaper Rash, Moisturizing Skin Protectant with Vitamins A & D, Healing Skin Ointment for Dry and Cracked Skin 16 oz

Desitin Daily Defense Baby Diaper Rash Cream with 13% Zinc Oxide, Barrier Cream to Treat, Relieve & Prevent Diaper Rash, Hypoallergenic, Dye-, Phthalate- & Paraben-Free, 16 oz

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Desitin Daily Defense Baby Diaper Rash Cream with 13% Zinc Oxide, Barrier Cream to Treat, Relieve & Prevent Diaper Rash, Hypoallergenic, Dye-, Phthalate- & Paraben-Free, 16 oz

Babo Botanicals Sensitive Baby Zinc Diaper Cream With Colloidal Oatmeal, Shea and Cocoa Butter, Fragrance-Free - 3 Oz

Babo Botanicals Sensitive Baby Zinc Diaper Cream With Colloidal Oatmeal, Shea and Cocoa Butter, Fragrance-Free - 3 Oz

The Honest Company Hypoallergenic Diaper Rash Cream, Moisturizing, Calming Zinc Oxide Ointment, NEA Recognized Cruelty-Free, 2.5 oz

The Honest Company Hypoallergenic Diaper Rash Cream, Moisturizing, Calming Zinc Oxide Ointment, NEA Recognized Cruelty-Free, 2.5 oz

Desitin Maximum Strength Baby Diaper Rash Cream, 40% Zinc Oxide, Hypoallergenic No Added Parabens & Dyes, Protects & Relieves Baby’s Skin for Up to 12 Hours, Prevents Diaper Rash, 4.8 oz Tube

Desitin Maximum Strength Baby Diaper Rash Cream, 40% Zinc Oxide, Hypoallergenic No Added Parabens & Dyes, Protects & Relieves Baby’s Skin for Up to 12 Hours, Prevents Diaper Rash, 4.8 oz Tube

Boudreaux’s Butt Paste Max Strength Diaper Rash Cream for Baby, Ointment With Zinc Oxide, 4 oz Tube

Boudreaux’s Butt Paste Max Strength Diaper Rash Cream for Baby, Ointment With Zinc Oxide, 4 oz Tube

A+D Original Diaper Rash Ointment Prevents & Treats Diaper Rash, Moisturizing Skin Protectant with Vitamins A & D, Healing Skin Ointment for Dry and Cracked Skin 4oz

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