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Best nano hydroxyapatite toothpastes - Holiday Sale 2025

Last Updated - December 14, 2025

1
Best Choice

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Our rankings are cleverly generated from the algorithmic analysis of thousands of customer reviews about products, brands, merchant’s customer service level, popularity, trends and more. The rankings reflect our opinion and should be a good starting point for shopping.

APAGARD

Apagard Premio Toothpaste 105g / 3.7 oz | Nano Hydroxyapatite High Blending, Brightening Toothpaste (Set of 3) 3-Pack 2023 Version

APAGARD

$38.75

More Details
Main highlights
- For the best effect from nano-mHAP toothpaste, we recommend that you (1) Place a small amount (1-1.5 cm) on a toothbrush. (2) Brush your teeth and gums gently but meticulously for about 3-5 minutes, ideally after each meal (3 times/day is recommended) (3) Rinse lightly and spit out after brushing, so nano-mHAP remaining will enrich your saliva and continue its work.
- APAGARD, Japan's leading toothpaste series for naturally beautiful teeth, is now available in the US. Discover the secret of naturally beautiful teeth from Japan. Contains Sangi's original nano-hydroxyaptite (nano-mHAP), almost the same substance as the hydroxyapatite that our teeth are made of, first synthesized in the 1970s by Sangi Co., Ltd
- APAGARD cleans the teeth and helps remove plaque with regular brushing.
- APAGARD M-plus is the standard, classic version and longest-selling product in the APAGARD range. It offers an all-around balance between natural whiteness enhancement, breath care, and stain control, and is suited for all ages, coming in a higher volume package, ideal for family use.
$38.75
2
Best Value
11% Off

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Our rankings are cleverly generated from the algorithmic analysis of thousands of customer reviews about products, brands, merchant’s customer service level, popularity, trends and more. The rankings reflect our opinion and should be a good starting point for shopping.

Boka
11% Off

Boka Fluoride Free Toothpaste, Nano Hydroxyapatite Toothpaste, Appropriate for Sensitive Teeth - for Adult, Kids Oral Care - Ela Mint Flavor, 4 Fl Oz 3Pk US Manufactured

Boka

$31.99

$35.99
(11% Off)

More Details
Main highlights
- TASTE THE ELA MINT FUSION: A delightful fusion of refreshing mint, antioxidant-rich green tea, with a hint of cardamom. The invigorating mint leaves your breath feeling fresh & revitalized, with just a touch of cardamom adding a unique, yet welcome twist to your brushing experience. Say goodbye to the bland & mundane - say hello to a toothpaste flavor that excites your taste buds every time you brush.
- FREE FROM THE BAD STUFF: No Fluoride, Sulfates, Parabens, Artificial Flavors, or Colors. We believe in keeping it simple and clean, offering you an effective and safe toothpaste option.
- ENAMEL CARE: Our proprietary and innovative formula includes Nano-hydroxyapatite (n-Ha) - a biometric mineral form of the same ingredient that naturally makes up 97% of your teeth material and 70% of your dentin. n-Ha has been the subject of significant research for decades with a wide variety of potential benefits across dentistry and oral care.
- BIOCOMPATIBLE: Free from Fluoride, Sulfates, Parabens & Artificial Flavors & Colors - we meticulously crafted our product to be biocompatible, ensuring it’s safe for daily use and non-toxic when used as directed. A perfect way to take your oral hygiene routine to the next level!
- APPROPRIATE FOR SENSITIVE TEETH: Gentle yet effective, it provides a soothing and refreshing experience for the whole family. Embrace an oral care routine designed for a luxurious experience.
$31.99
$35.99 (11% Off)
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Our rankings are cleverly generated from the algorithmic analysis of thousands of customer reviews about products, brands, merchant’s customer service level, popularity, trends and more. The rankings reflect our opinion and should be a good starting point for shopping.

ZODENIS

Hydroxyapatite Toothpaste 7.5%, 2Pcs Nano Hydroxyapatite Toothpaste for Enamel Protection and Tooth Strengthening, Gentle Mint, Fresh Breath, Daily Use for Oral Health

ZODENIS

$16.99

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Main highlights
- 【Natural Mint for Fresh Breath Hydroxyapatite Toothpastes】- Infused with natural peppermint, this nano hydroxyapatite toothpaste ensures 12-hour fresh breath and a refreshing clean, free from artificial flavors or sweeteners.
- 【Nano Hydroxyapatite Toothpaste Enamel Restoration & Defense】- Our nano hydroxyapatite formula actively rebuilds weakened enamel while creating a protective shield against acid attacks. Clinically proven to reduce cavity formation by 45% and repair early erosion marks within weeks of regular use. Our 7.5% hydroxyapatite toothpaste strengthens and remineralizes tooth enamel, preventing erosion and daily wear. Ideal for restoring and maintaining healthy teeth.
- 【Gentle & Fluoride-Free Formula , Sensitivity-Soothing】- Perfect for sensitive teeth, Enjoy a fluoride-free toothpaste that provides advanced enamel protection, ensuring safe, effective care without the need for harsh chemicals.
- 【Daily Oral Care Essential】- This fluoride-free formula with 7.5% nano-hydroxyapatite reduces sensitivity within 2-5 days, gradually whitens stains over 2-4 weeks, and repairs enamel micro-damage in 4-8 weeks. Safe for ages 6+ and orthodontic care. For optimal results, brush twice daily for 2 minutes and avoid rinsing immediately after use
- 【Advanced 7.5% Hydroxyapatite Toothpaste】- This hydroxyapatite toothpaste 7.5% is powered by nano hydroxyapatite, a natural mineral that repairs enamel, reduces sensitivity, and protects against cavities for long-term oral health.
$16.99
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Our rankings are cleverly generated from the algorithmic analysis of thousands of customer reviews about products, brands, merchant’s customer service level, popularity, trends and more. The rankings reflect our opinion and should be a good starting point for shopping.

Mouthology

Mouthology 10% Nano Hydroxyapatite Toothpaste (Fluoride Free), Whitening*, Supports Enamel Care*, Appropriate for Sensitive Teeth*, SLS Free, Xylitol nHA Toothpaste for Adults, Mint 4oz (USA Made)

Mouthology

$12.99

More Details
Main highlights
- Whitening* = *Based on the cleaning and polishing action of the toothpaste; no claim of altering tooth color or providing a bleaching effect.
- WHY 10% SPECIFICALLY?: Unlike other brands that hide their Nano-Hydroxyapatite percentages, our toothpaste contains the full 10% Nano Hydroxyapatite—the optimal amount concluded my most scientific studies. Too little is ineffective, and too much nHA starts to aggregate (or "clump" together) also reducing efficacy.
- THAT CLEAN DENTIST FEELING: Say goodbye to harsh bleaching agents. Our nano hydroxyapatite toothpaste gently polishes, leaving you with a glossier, smoother "tooth feel" without causing sensitivity.
- Supports Enamel Care* = **Based on the properties of nano-hydroxyapatite as reported in published research; no claim of specific clinical outcomes for this product.
- MADE IN USA WITH CLEAN INGREDIENTS: Made in the USA with premium, globally sourced ingredients. Our toothpaste is fluoride-free, SLS-free, with birch xylitol to promote oral health. No artificial colors or flavors. No Triclosan. No Titanium Dioxide. Just clean, gentle care for your mouth.
- FLUORIDE FREE & SAFE FOR ALL AGES: Our nano hydroxyapatite toothpaste is completely fluoride-free, offering a safe alternative for those looking to avoid the negative health concerns of fluoride. Our nHa toothpaste is made with biocompatible ingredients, safe if swallowed and recommended by dentists nation-wide.
- 10% NANO-HYDROXYAPATITE: Our toothpaste features 10% nano-hydroxyapatite (n-HA), a calcium-based compound used in Japan for decades in oral care. Known for its smooth feel and gentle cleaning, n-HA is an alternative to fluoride for those who prefer fluoride-free options. n-HA is a remarkable biomaterial that comprises 60-70% of bone mass and an astounding 96% of tooth enamel, making it the hardest substance in the human body.
$12.99
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Our rankings are cleverly generated from the algorithmic analysis of thousands of customer reviews about products, brands, merchant’s customer service level, popularity, trends and more. The rankings reflect our opinion and should be a good starting point for shopping.

Generic

Hydroxyapatite Toothpaste 9.9%, 2PCS Nano Hydroxyapatite Toothpaste (Fluoride Free) for Enamel Protection and Tooth Strengthening –Gentle Mint, Fresh Breath, Daily Use for Oral Care

Generic

$16.99

More Details
Main highlights
- [Nature Mint flavor Fresh Breath] - Infused with a refreshing mint flavor to neutralize odors and provide long-lasting freshness. Let the refreshing mint elevate your breath, leaving it fresh and revitalized.
- [Nano Hydroxyapatite Toothpaste Repair And Protect Tooth Ename] - Hydroxyapatite is the main component of tooth enamel, which can effectively fill the tiny cracks on the surface of the teeth and repair tooth damage caused by wear and tear or acid erosion. Reducing the risk of cavities and erosion. It promotes long-term oral health by strengthening enamel and preventing daily wear and tear.
- [Fluoride-Free & Natural Formula,Effectively Removing Teeth Stains] - Enjoy safe, effective care with this fluoride-free nano hydroxyapatite toothpaste. Free from harsh chemicals, it provides advanced enamel protection while being gentle on your teeth and gums. And effectively removing surface stains and restoring the natural of your teeth.
- [9.9% Hydroxyapatite Toothpaste Gentle For Sensitive Teeths] - Harnessing the strength of Nano Hydroxyapatite (NHA), This toothpaste is Gentle yet effective, Specially designed to cater to those with sensitive teeth. The gentle hydroxyapatite formula creates a protective barrier to alleviate discomfort from hot, cold, sweet, and acidic stimuli. It provides a gentle and refreshing experience without compromising on dental benefits. Say goodbye to sensitivity.
- [ Daily Oral Care Essential]- This fluoride-free formula with 10% nano-hydroxyapatite reduces sensitivity within 2-5 days, gradually reduce stains over 2-4 weeks, and repairs enamel micro-damage in 4-8 weeks. Safe for ages 6+ and orthodontic care. For optimal results, brush twice daily for 2 minutes and avoid rinsing immediately after use
$16.99

Best nano hydroxyapatite toothpastes - Holiday Sale 2025

Apagard Premio Toothpaste 105g / 3.7 oz | Nano Hydroxyapatite High Blending, Brightening Toothpaste (Set of 3) 3-Pack 2023 Version

Boka Fluoride Free Toothpaste, Nano Hydroxyapatite Toothpaste, Appropriate for Sensitive Teeth - for Adult, Kids Oral Care - Ela Mint Flavor, 4 Fl Oz 3Pk US Manufactured

Hydroxyapatite Toothpaste 7.5%, 2Pcs Nano Hydroxyapatite Toothpaste for Enamel Protection and Tooth Strengthening, Gentle Mint, Fresh Breath, Daily Use for Oral Health

Mouthology 10% Nano Hydroxyapatite Toothpaste (Fluoride Free), Whitening, Supports Enamel Care, Appropriate for Sensitive Teeth*, SLS Free, Xylitol nHA Toothpaste for Adults, Mint 4oz (USA Made)

Hydroxyapatite Toothpaste 9.9%, 2PCS Nano Hydroxyapatite Toothpaste (Fluoride Free) for Enamel Protection and Tooth Strengthening –Gentle Mint, Fresh Breath, Daily Use for Oral Care

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Best nano hydroxyapatite toothpastes - Holiday Sale 2025

Apagard Premio Toothpaste 105g / 3.7 oz | Nano Hydroxyapatite High Blending, Brightening Toothpaste (Set of 3) 3-Pack 2023 Version

Boka Fluoride Free Toothpaste, Nano Hydroxyapatite Toothpaste, Appropriate for Sensitive Teeth - for Adult, Kids Oral Care - Ela Mint Flavor, 4 Fl Oz 3Pk US Manufactured

Hydroxyapatite Toothpaste 7.5%, 2Pcs Nano Hydroxyapatite Toothpaste for Enamel Protection and Tooth Strengthening, Gentle Mint, Fresh Breath, Daily Use for Oral Health

Mouthology 10% Nano Hydroxyapatite Toothpaste (Fluoride Free), Whitening*, Supports Enamel Care*, Appropriate for Sensitive Teeth*, SLS Free, Xylitol nHA Toothpaste for Adults, Mint 4oz (USA Made)

Hydroxyapatite Toothpaste 9.9%, 2PCS Nano Hydroxyapatite Toothpaste (Fluoride Free) for Enamel Protection and Tooth Strengthening –Gentle Mint, Fresh Breath, Daily Use for Oral Care

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Ollie Clean Mint Nano Hydroxyapatite Toothpaste for Teeth Whitening, 10% Hydroxyapatite Formula, 4oz

2Pcs Hydroxyapatite Toothpaste, Deep Cleaning Toothpaste, Advanced Enamel Protection, Fluoride-Free Formula with Gentle Mint, for Sensitive Teeth (120g)

APAGARD® PREMIO, Sangi's Nano-Hydroxyapatite Toothpaste for Naturally Whiter Teeth, No Fluoride, For family use, 105g / 3.7 Oz, Double Mint, Pack of 2

IZKUT 10% Nano Hydroxyapatite Toothpaste: Fluoride Free Natural Whitening Toothpaste for Sensitive Teeth, Enamel Support, Plaque Remover, SLS Free, Fresh Mint Flavor, Adults & Kids, 4 oz (Pack of 2)

MasterMedi Nano Hydroxyapatite Toothpaste (Inspired by 10% nHA Formulas), Fluoride-Free, Whitening, Sensitive Teeth Care, Enamel Support, SLS Free, Xylitol, Magic Mint, 4 Oz (Pack of 2)

Boka Fluoride Free Toothpaste, Nano Hydroxyapatite Toothpaste, Appropriate for Sensitive Teeth - for Adult, Kids Oral Care - Ela Mint Flavor, 4 Fl Oz 1Pk US Manufactured

Boka Fluoride Free Toothpaste, Nano Hydroxyapatite Toothpaste, Appropriate for Sensitive Teeth, for Adult, Kids Oral Care - Whitening* Refresh Mint, 4 Fl Oz 1Pk US Manufactured

Davids Hydroxi Fluoride Free Nano Hydroxyapatite Whitening + Enamel Health Toothpaste, Antiplaque, Fresh Breath, Remineralizing, SLS Free, Natural Peppermint, 4 oz, Made in USA

7.5% Hydroxyapatite Toothpaste – Fluoride-Free Whitening & Enamel Support, Gentle Nano Formula for Sensitive Teeth, Fresh Mint, Natural Daily Care

Davids Hydroxi Fluoride Free Nano Hydroxyapatite Toothpaste for Remineralizing Enamel & Sensitive Relief, Whitening, Antiplaque, SLS Free, Natural Peppermint, 4 oz, Made in USA

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Mouthology 10% Nano Hydroxyapatite Toothpaste (Fluoride Free), Whitening, Supports Enamel Care, Appropriate for Sensitive Teeth*, SLS Free, Xylitol nHA Toothpaste for Adults, Mint 4oz (USA Made)