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Best bed bug spray yets - Holiday Sale 2025

Last Updated - December 14, 2025

1
Best Choice

✖
Our rankings are cleverly generated from the algorithmic analysis of thousands of customer reviews about products, brands, merchant’s customer service level, popularity, trends and more. The rankings reflect our opinion and should be a good starting point for shopping.

HARRIS

Harris Toughest Bed Bug Killer, Liquid Spray with Odorless and Non-Staining Extended Residual Kill Formula (Gallon)

HARRIS

$59.99

More Details
Main highlights
- Trusted Brand Since 1922: Trusted Brand Since 1922: Jobs done right, in and around the home for over a century. Harris is America's oldest EPA registered Pest Brand!
- Tough Formula: Formulated for maximum strength, this Black Label bed bug spray is a powerful solution, designed to kill even the most persistent and pesticide-resistant bed bugs.
- Long-Lasting Residual Protection: Provides extended control for up to 16 weeks after application, making it ideal for long-term bed bug management and prevention.
- Kills Bed Bugs, Eggs, and Pyrethroid-Resistant Strains: Effectively eliminates all life stages of bed bugs, including hard-to-kill eggs and resistant strains that survive standard treatments.
- EPA Registered for Indoor Use: Registered with the EPA (Reg. No. 1021-2597-3) for safe use in homes, apartments, hotels, and other residential environments. Use as directed.
- Complete Home Coverage: Designed for use in bedrooms, living spaces, baseboards, cracks, and crevices to target bed bug hiding spots throughout the entire home.
$59.99
2
12% Off

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Our rankings are cleverly generated from the algorithmic analysis of thousands of customer reviews about products, brands, merchant’s customer service level, popularity, trends and more. The rankings reflect our opinion and should be a good starting point for shopping.

MGK
12% Off

Bedlam Bed Bugs Spray (2 Spray Cans)

MGK

$34.98

$39.99
(12% Off)

More Details
Main highlights
- The Same Products Pest Control Companies Use
- Target pests: Bed Bugs, Adult Lice and Nymphs, Ticks, Fleas, Dust Mites
- Bedlam will not stain water-safe fabrics and surfaces.
- Bedlam kills on contact and provides residual control.
- Bedlam is water-based and non-irritating - may be used on bedding and fabric.
$34.98
$39.99 (12% Off)
3
13% Off

✖
Our rankings are cleverly generated from the algorithmic analysis of thousands of customer reviews about products, brands, merchant’s customer service level, popularity, trends and more. The rankings reflect our opinion and should be a good starting point for shopping.

Ortho
13% Off

Ortho Home Defense Max Bed Bug, Flea and Tick Killer with Comfort Wand, Bed Bug Spray, Kills Bed Bug Eggs, Fleas and Ticks, 1 gal.

Ortho

$19.97

$22.99
(13% Off)

More Details
Main highlights
- Use this indoor bug killer as a spot treatment around bed frames, baseboards and mattress seams, tufts and folds
- This bed bug spray kills even the toughest bed bugs (pyrethroid-resistant bed bugs)
- Ortho Home Defense Max Bed Bug, Flea & Tick Killer is a Step 2 product in the Ortho Bed Bug Solution System; use with Step 1: Detect and Trap and Step 3: Cracks and Crevices products for best results
- Kill bed bugs, bed bug eggs, fleas and ticks with Ortho Home Defense Max Bed Bug, Flea & Tick Killer
- Apply insect spray using the included Comfort Wand to target tight and hard-to-reach places where bed bugs hide
$19.97
$22.99 (13% Off)
4

✖
Our rankings are cleverly generated from the algorithmic analysis of thousands of customer reviews about products, brands, merchant’s customer service level, popularity, trends and more. The rankings reflect our opinion and should be a good starting point for shopping.

EcoVenger

Bed Bug Killer 16 oz EcoVenger by EcoRaider, 100% Kill Efficacy, Bedbugs & Mites, Kills Eggs & The Resistant, Lasting Protection, USDA BIO-Certified, Plant Extract Based & Non-Toxic, Child & Pet Safe

EcoVenger

$19.95

More Details
Main highlights
- USDA FIELD-TESTED & PROVEN: Vetted through the USDA IR4 PHP Program and field-tested by research entomologists. Recommended for sensitive environments, it's a trusted solution for eliminating bed bugs in public housing and other vulnerable settings.
- UNDERSTANDING PRODUCT BATCH IDS: You may see two different types of product IDs on products you receive. A "Manufacture Batch #" indicates the date the product was manufactured. A "Best Use Before" date suggests the optimal time frame for using the product for best performance. If you have any questions, please contact the seller directly.
- NON-TOXIC, SAFE & ECO-FRIENDLY: Certified as a USDA BioBased insecticide and dermatologically safe. This product is child and pet-friendly, making it safe to use directly on mattresses and box springs without worry.
- KILLS ALL STAGES, INCLUDING RESISTANT BED BUGS: This formula kills bed bug adults and nymphs on contact with 100% efficacy. It's also proven to eliminate bed bugs resistant to traditional pesticides and has the highest performance in destroying bed bug eggs.
- INGREDIENTS: Geraniol, Cedarwood oil, Sodium Lauryl Sulfate, Glyceryl dicaprylate, Silica hydrate, Glyceryl monooleate and water.
- HIGHLY EFFECTIVE, PLANT-POWERED BED BUG KILLER: EcoVenger Bed Bug Killer uses a patented blend of botanical insecticidal compounds to combat tough insects. A published university study ranks it as the #1 most effective natural product against bed bugs among 12 products tested, outperforming traditional pesticides.
- EXTENDED DRY RESIDUAL PROTECTION: A university study demonstrates that EcoVenger's residual formula provides two weeks of extended protection against bed bugs, even after it has dried, offering long-term peace of mind.
$19.95
5
Best Value
32% Off

✖
Our rankings are cleverly generated from the algorithmic analysis of thousands of customer reviews about products, brands, merchant’s customer service level, popularity, trends and more. The rankings reflect our opinion and should be a good starting point for shopping.

HARRIS
32% Off

HARRIS White Label Bed Bug Killer, Liquid Spray with Odorless and Non-Staining Extended Residual Kill Formula (32oz)

HARRIS

$17.96

$26.43
(32% Off)

More Details
Main highlights
- TRUSTED BRAND SINCE 1922: Harris has been providing effective pest control and insect management solutions for over a century, trusted by professionals and homeowners alike.
- TOUGH FORMULA: Formulated for maximum strength, this Black Label bed bug spray is a powerful solution, designed to kill even the most persistent and pesticide-resistant bed bugs.
- ODORLESS & NON-STAINING: Specially formulated to be scent-free and won’t stain mattresses, furniture, carpets, or bedding—ideal for indoor use without lingering smells or damage.
- LONG-LASTING RESIDUAL PROTECTION: Provides extended control for up to 16 weeks after application, making it ideal for long-term bed bug management and prevention.
- KILLS BED BUGS, EGGS, AND PYRETHOID-RESISTANT STRAINS: Effectively eliminates all life stages of bed bugs, including hard-to-kill eggs and resistant strains that survive standard treatments.
- EPA REGISTERED FOR INDOOR USE: Registered with the EPA (Reg. No. 1021-2597-3) for safe use in homes, apartments, hotels, and other residential environments. Use as directed.
- COMPLETE HOME COVERAGE: Designed for use in bedrooms, living spaces, baseboards, cracks, and crevices to target bed bug hiding spots throughout the entire home.
$17.96
$26.43 (32% Off)

Best bed bug spray yets - Holiday Sale 2025

Harris Toughest Bed Bug Killer, Liquid Spray with Odorless and Non-Staining Extended Residual Kill Formula (Gallon)

Bedlam Bed Bugs Spray (2 Spray Cans)

Ortho Home Defense Max Bed Bug, Flea and Tick Killer with Comfort Wand, Bed Bug Spray, Kills Bed Bug Eggs, Fleas and Ticks, 1 gal.

Bed Bug Killer 16 oz EcoVenger by EcoRaider, 100% Kill Efficacy, Bedbugs & Mites, Kills Eggs & The Resistant, Lasting Protection, USDA BIO-Certified, Plant Extract Based & Non-Toxic, Child & Pet Safe

HARRIS White Label Bed Bug Killer, Liquid Spray with Odorless and Non-Staining Extended Residual Kill Formula (32oz)

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